Boosting checkpoint immunotherapy with biomaterials
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …
Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …
Recent progress of metal‐based nanomaterials with anti‐tumor biological effects for enhanced cancer therapy
H Lei, Z Pei, C Jiang, L Cheng - Exploration, 2023 - Wiley Online Library
Metal‐based nanomaterials have attracted broad attention recently due to their unique
biological physical and chemical properties after entering tumor cells, namely biological …
biological physical and chemical properties after entering tumor cells, namely biological …
Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …
oncology treatments, emerges in the current management of cancer. A growing number of …
A Self‐Reporting Fluorescent Salicylaldehyde–Chlorambucil Conjugate as a Type‐II ICD Inducer for Cancer Vaccines
M Zhang, X Jin, M Gao, Y Zhang… - Advanced Materials, 2022 - Wiley Online Library
Immunogenic cell death (ICD) can activate the anticancer immune response and is highly
attractive to improve cancer treatment efficacy. ICD is closely related to endoplasmic …
attractive to improve cancer treatment efficacy. ICD is closely related to endoplasmic …
[HTML][HTML] Engineered tumor cell-derived vaccines against cancer: The art of combating poison with poison
X Zhang, H Cui, W Zhang, Z Li, J Gao - Bioactive Materials, 2023 - Elsevier
Tumor vaccination is a promising approach for tumor immunotherapy because it presents
high specificity and few side effects. However, tumor vaccines that contain only a single …
high specificity and few side effects. However, tumor vaccines that contain only a single …
Biosynthetic dendritic cell-exocytosed aggregation-induced emission nanoparticles for synergistic photodynamic immunotherapy
H Cao, H Gao, L Wang, Y Cheng, X Wu, X Shen… - ACS …, 2022 - ACS Publications
Dendritic cell (DC)-derived small extracellular vesicles (DEVs) are recognized as a highly
promising alternative to DC vaccines; however, the clinical testing of DEV-based …
promising alternative to DC vaccines; however, the clinical testing of DEV-based …
Metal‐cyclic dinucleotide nanomodulator‐stimulated STING signaling for strengthened radioimmunotherapy of large tumor
D Wang, T Nie, C Huang, Z Chen, X Ma, W Fang… - Small, 2022 - Wiley Online Library
Combined treatment of immunotherapy and radiotherapy shows promising therapeutic
effects for the regression of a variety of cancers. However, even multi‐modality therapies …
effects for the regression of a variety of cancers. However, even multi‐modality therapies …
Four ounces can move a thousand pounds: the enormous value of nanomaterials in tumor immunotherapy
Z Chen, Z Yue, K Yang, C Shen… - Advanced …, 2023 - Wiley Online Library
The application of nanomaterials in healthcare has emerged as a promising strategy due to
their unique structural diversity, surface properties, and compositional diversity. In particular …
their unique structural diversity, surface properties, and compositional diversity. In particular …
Melatonin as a regulator of apoptosis in leukaemia: molecular mechanism and therapeutic perspectives
A Mafi, H Rismanchi, Y Gholinezhad… - Frontiers in …, 2023 - frontiersin.org
Leukaemia is a dangerous malignancy that causes thousands of deaths every year
throughout the world. The rate of morbidity and mortality is significant despite many …
throughout the world. The rate of morbidity and mortality is significant despite many …