Genome organization and genomics in Chlamydia: whole genome sequencing increases understanding of chlamydial virulence, evolution, and phylogeny

LDW Luu, V Kasimov, S Phillips, GSA Myers… - Frontiers in cellular …, 2023 - frontiersin.org
The genus Chlamydia contains important obligate intracellular bacterial pathogens to
humans and animals, including C. trachomatis and C. pneumoniae. Since 1998, when the …

COG database update: focus on microbial diversity, model organisms, and widespread pathogens

MY Galperin, YI Wolf, KS Makarova… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Clusters of Orthologous Genes (COG) database, also referred to as the
Clusters of Orthologous Groups of proteins, was created in 1997 and went through several …

Aberrant Bodies: An Alternative Metabolic Homeostasis Allowing Survivability?

T Kozusnik, SE Adams, G Greub - Microorganisms, 2024 - mdpi.com
The Chlamydiae phylum is comprised of obligate intracellular bacteria including human
pathogens such as Chlamydia trachomatis and lesser-known Chlamydia-related bacteria …

Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor

Y Huang, W Wurihan, B Lu, Y Zou, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living
bacteria, the transcriptomic reprogramming is mediated by increased DNA-binding activity of …

Copper oxide nanoparticles induce non-alcoholic fatty liver disease by disrupting bile acid homeostasis and perturbing the intestinal microbial homeostasis

M Jiang, X Tao, Y Pang, Z Qin, E Song… - Journal of Hazardous …, 2024 - Elsevier
The wide application of copper oxide nanoparticles (CuO NPs) in various fields such as
medicine, food, agriculture, and animal husbandry can result in direct or indirect oral …

Conservation of the glycogen metabolism pathway underlines a pivotal function of storage polysaccharides in Chlamydiae

M Colpaert, D Kadouche, M Ducatez, T Pillonel… - Communications …, 2021 - nature.com
The order Chlamydiales includes obligate intracellular pathogens capable of infecting
mammals, fishes and amoeba. Unlike other intracellular bacteria for which intracellular …

OpenGenomeBrowser: a versatile, dataset-independent and scalable web platform for genome data management and comparative genomics

T Roder, S Oberhänsli, N Shani, R Bruggmann - BMC genomics, 2022 - Springer
Background As the amount of genomic data continues to grow, there is an increasing need
for systematic ways to organize, explore, compare, analyze and share this data. Despite this …

The Chlamydia-related Waddlia chondrophila encodes functional type II toxin-antitoxin systems

S Ardissone, G Greub - Applied and Environmental Microbiology, 2024 - Am Soc Microbiol
Bacterial toxin-antitoxin (TA) systems are widespread in chromosomes and plasmids of free-
living microorganisms, but only a few have been identified in obligate intracellular species …

zDB: bacterial comparative genomics made easy

B Marquis, T Pillonel, A Carrara, C Bertelli - Msystems, 2024 - journals.asm.org
The analysis and comparison of genomes rely on different tools for tasks such as annotation,
orthology prediction, and phylogenetic inference. Most tools are specialized for a single task …

[HTML][HTML] Pangenome-Wide Association Study in the Chlamydiaceae Family Reveals Key Evolutionary Aspects of Their Relationship with Their Hosts

R Salgado-Morales, K Barba-Xochipa… - International Journal of …, 2024 - mdpi.com
The Chlamydiaceae are a family of obligate intracellular bacteria known for their unique
biphasic developmental cycle. Chlamydial are associated with various host organisms …