Objective To evaluate cardiovascular and metabolic features of offspring conceived by in
vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI). Design Literature review and …

BACKGROUND Since the birth of the first baby using IVF technology in 1978, over 10 million
children have been conceived via ART. Although most aspects of ARTs were developed in …

Metabolic syndrome is reaching epidemic proportions, particularly in developing countries.
In this review, we explore the concept—based on the developmental-origin-of-health-and …

Exposure of the embryo or fetus to perturbations in utero can result in intrauterine growth
restriction, a primary risk factor for the development of adult disease. However, despite …

Background Some earlier studies have found indications of significant changes in
cardiometabolic risk factors in children born after assisted reproductive technology (ART) …

Background Vitamin D deficiency in women diagnosed with polycystic ovary syndrome
(PCOS) remarkably decreases the chance of pregnancy, which might be related to its impact …

BACKGROUND The subject of epigenetic risk of assisted reproduction treatment (ART),
initiated by reports on an increase of children with the Beckwith–Wiedemann imprinting …

Early stages of mammalian embryonic development are now known to be very sensitive to
their microenvironment, with long term effects on fetal, postnatal, and adult health, thus …

In vitro fertilization (IVF) may influence the metabolic health of children. However, in humans,
it is difficult to separate out the relative contributions of genetics, environment, or the process …

The Developmental Origins of Health and Disease hypothesis holds that alterations to
homeostasis during critical periods of development can predispose individuals to adult …