CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond

AF Russo, DL Hay - Physiological reviews, 2023 - journals.physiology.org
Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

Migraine: a review on its history, global epidemiology, risk factors, and comorbidities

P Amiri, S Kazeminasab, SA Nejadghaderi… - Frontiers in …, 2022 - frontiersin.org
Migraine affects more than one billion individuals each year across the world, and is one of
the most common neurologic disorders, with a high prevalence and morbidity, especially …

Migraine and diet

P Gazerani - Nutrients, 2020 - mdpi.com
Migraine is characterized by recurrent attacks of disabling headaches, often accompanied
by sensory and motor disturbances. Clinical manifestations of migraine are influenced by …

Calcitonin gene-related peptide (CGRP): a new target for migraine

AF Russo - Annual review of pharmacology and toxicology, 2015 - annualreviews.org
Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …

From transformation to chronification of migraine: pathophysiological and clinical aspects

M Torres-Ferrús, F Ursitti, A Alpuente… - The journal of headache …, 2020 - Springer
Chronic migraine is a neurological disorder characterized by 15 or more headache days per
month of which at least 8 days show typical migraine features. The process that describes …

Genetics of migraine: insights into the molecular basis of migraine disorders

HG Sutherland, LR Griffiths - … : The Journal of Head and Face …, 2017 - Wiley Online Library
Migraine is a complex, debilitating neurovascular disorder, typically characterized by
recurring, incapacitating attacks of severe headache often accompanied by nausea and …

[HTML][HTML] Migraine, brain glucose metabolism and the “neuroenergetic” hypothesis: a scoping review

L Del Moro, E Rota, E Pirovano, I Rainero - The Journal of pain, 2022 - Elsevier
Increasing evidence suggests that migraine may be the result of an impaired brain glucose
metabolism. Several studies have reported brain mitochondrial dysfunction, impaired brain …

Exploring the hereditary nature of migraine

C Bron, HG Sutherland, LR Griffiths - Neuropsychiatric Disease and …, 2021 - Taylor & Francis
Migraine is a common neurological disorder which affects 15–20% of the population; it has a
high socioeconomic impact through treatment and loss of productivity. Current forms of …

The association between stress and headache: A longitudinal population-based study

SH Schramm, S Moebus, N Lehmann, U Galli… - …, 2015 - journals.sagepub.com
Introduction We studied the association between stress intensity and headache frequency
for tension-type headache (TTH), migraine and migraine with coexisting TTH (MigTTH) …

Epigenetic connection of the calcitonin gene-related peptide and its potential in migraine

M Fila, A Sobczuk, E Pawlowska, J Blasiak - International journal of …, 2022 - mdpi.com
The calcitonin gene-related peptide (CGRP) is implicated in the pathogenesis of several
pain-related syndromes, including migraine. Targeting CGRP and its receptor by their …