All cells sense and integrate mechanical and biochemical cues from their environment to
orchestrate organismal development and maintain tissue homeostasis …

Traumatic brain injury (TBI) is distinct from other neurological disorders because it is
induced by a discrete event that applies extreme mechanical forces to the brain. This review …

A growing body of work describes how physical forces in and around cells affect their
growth, proliferation, migration, function and differentiation into specialized types. How cells …

Traumatic brain injuries, the leading cause of death and disability in children and young
adults, are the result of a rapid acceleration or impact of the head. In recent years, a global …

Research on the mechanical properties of brain tissue has gradually deepened recently.
Two indentation protocols were used here to characterize the mechanical properties of …

Brain tissue is one of the most complex and softest tissues in the human body. Due to its
ultrasoft and biphasic nature, it is difficult to control the deformation state during …

Brain maturation and neurological diseases are intricately linked to microstructural changes
that inherently affect the brain's mechanical behavior. Animal models are frequently used to …

Traumatic brain injury (TBI) has become a recent focus of biomedical research with a
growing international effort targeting material characterization of brain tissue and …

Traumatic brain injury (TBI) is an important cause of mortality and morbidity worldwide. Finite
element models of the human head are used widely to simulate TBI loading scenarios, to …

Concussion is associated with a myriad of deleterious immediate and long-term
consequences. Yet the molecular mechanisms and genetic targets promoting the selective …