Systems metabolic engineering of microorganisms for food and cosmetics production

KR Choi, SY Lee - Nature Reviews Bioengineering, 2023 - nature.com
The demand for sustainable and environmentally friendly sources of foods and cosmetics is
increasing owing to concerns about the rapid growth of the global population and climate …

[HTML][HTML] Modular engineering for microbial production of carotenoids

C Li, CA Swofford, AJ Sinskey - Metabolic Engineering Communications, 2020 - Elsevier
There is an increasing demand for carotenoids due to their applications in the food, flavor,
pharmaceutical and feed industries, however, the extraction and synthesis of these …

Harnessing bioengineered microbes as a versatile platform for space nutrition

B Llorente, TC Williams, HD Goold, IS Pretorius… - Nature …, 2022 - nature.com
Human enterprises through the solar system will entail long-duration voyages and habitation
creating challenges in maintaining healthy diets. We discuss consolidating multiple sensory …

Complete and efficient conversion of plant cell wall hemicellulose into high-value bioproducts by engineered yeast

L Sun, JW Lee, S Yook, S Lane, Z Sun, SR Kim… - Nature …, 2021 - nature.com
Plant cell wall hydrolysates contain not only sugars but also substantial amounts of acetate,
a fermentation inhibitor that hinders bioconversion of lignocellulose. Despite the toxic and …

Engineering endogenous ABC transporter with improving ATP supply and membrane flexibility enhances the secretion of β-carotene in Saccharomyces cerevisiae

X Bu, JY Lin, J Cheng, D Yang, CQ Duan… - Biotechnology for …, 2020 - Springer
Background Product toxicity is one of the bottlenecks for microbial production of biofuels,
and transporter-mediated biofuel secretion offers a promising strategy to solve this problem …

Synthetic biology: a new frontier in food production

S Shi, Z Wang, L Shen, H Xiao - Trends in Biotechnology, 2022 - cell.com
Concerns regarding food security arise from population growth, global warming, and
reduction in arable land. With advances in synthetic biology, food production by microbes is …

The beauty of biocatalysis: sustainable synthesis of ingredients in cosmetics

RS Heath, RE Ruscoe, NJ Turner - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 2015 up to July 2021 The market for cosmetics is consumer driven and the desire
for green, sustainable and natural ingredients is increasing. The use of isolated enzymes …

Dual regulation of lipid droplet-triacylglycerol metabolism and ERG9 expression for improved β-carotene production in Saccharomyces cerevisiae

X Bu, JY Lin, CQ Duan, MAG Koffas, GL Yan - Microbial Cell Factories, 2022 - Springer
Background The limitation of storage space, product cytotoxicity and the competition for
precursor are the major challenges for efficiently overproducing carotenoid in engineered …

Regulation of carotenoid degradation and production of apocarotenoids in natural and engineered organisms

MH Liang, YJ He, DM Liu, JG Jiang - Critical Reviews in …, 2021 - Taylor & Francis
Carotenoids are important precursors of a wide range of apocarotenoids with their functions
including: hormones, pigments, retinoids, volatiles, and signals, which can be used in the …

Engineering xylose metabolism in yeasts to produce biofuels and chemicals

JW Lee, S Yook, H Koh, CV Rao, YS Jin - Current Opinion in Biotechnology, 2021 - Elsevier
Xylose is the second most abundant sugar in lignocellulosic biomass. Efficient and rapid
xylose utilization is essential for the economic bioconversion of lignocellulosic biomass into …