Associations between blood type and disease have been studied since the early 1900s
when researchers determined that antibodies and antigens are inherited. In the 1950s, the …

Enzymes catalyze biochemical reactions and play critical roles in human health and
disease. Enzyme variants and deficiencies can lead to variable expression of glycans, which …

The International Society of Blood Transfusion Working Party on red cell immunogenetics
and blood group terminology convened during the International congress in Cancun, July …

Forssman blood group system is an independent new blood group system determined by
the ISBT after 2012. FORS antigen is a heterophile antigen. Escherichia coli and Shigella …

A wide variety of so-called natural antibodies (nAbs), ie immunoglobulins generated by B-1
cells, are directed to glycans. nAbs to glycans can be divided in three groups: 1) …

Humoral immunity to pathogens and other environmental challenges is paramount to
maintain normal health, and individuals lacking or unable to make antibodies are at risk …

Abstract Function—spacer—lipid (FSL) constructs are amphiphilic molecules that are able to
disperse in water and then self-assemble into cell membranes or onto solid surfaces …

Therapeutic cancer vaccines can be effective for treating patients, but clinical responses
vary considerably from patient to patient. Early indicators of a favorable response are crucial …

Background The GBGT1 gene encodes the globoside alpha-1, 3-N-
acetylgalactosaminyltransferase 1. This enzyme catalyzes the last step in the multi-step …

Antigens belonging to the P1PK, GLOB, and FORS blood group systems and the GLOB
blood group collection represent a closely related set of 13 glycosphingolipids (GSLs). They …