Cellular processes are typically carried out by protein complexes and functional modules.
Identifying them plays an important role for our attempt to reveal principles of cellular …

Background and scope Nowadays, centrality analysis has become a principal method for
identifying essential proteins in biological networks. Here we present CytoNCA, a Cytoscape …

In the post-genomic era, proteomics has achieved significant theoretical and practical
advances with the development of high-throughput technologies. Especially the rapid …

Studying the topology of a network is critical to inferring underlying dynamics such as
tolerance to failure, group behavior and spreading patterns. k-core decomposition is a well …

Identification of essential proteins is key to understanding the minimal requirements for
cellular life and important for drug design. The rapid increase of available protein-protein …

Grey wolf optimizer (GWO) is known as one of the recent popular metaheuristic algorithms
inspired from the social collaboration and team hunting activities of grey wolves in nature …

Cluster analysis of biological networks is one of the most important approaches for
identifying functional modules and predicting protein functions. Furthermore, visualization of …

Alcohol abuse and alcohol dependence are key factors in the development of alcohol use
disorder, which is a pervasive societal problem with substantial economic, medical, and …

Nowadays, cluster analysis of biological networks has become one of the most important
approaches to identifying functional modules as well as predicting protein complexes and …

Background Identification of protein complexes and functional modules from protein-protein
interaction (PPI) networks is crucial to understanding the principles of cellular organization …