Osteocytes and WNT: the mechanical control of bone formation

C Galli, G Passeri… - Journal of dental research, 2010 - journals.sagepub.com
Mechanical loading is of pivotal importance in the maintenance of skeletal homeostasis, but
the players involved in the transduction of mechanical stimuli to promote bone maintenance …

The genetic basis of craniofacial and dental abnormalities

T Kouskoura, N Fragou, M Alexiou, N John… - Schweizerische …, 2011 - boris.unibe.ch
The embryonic head development, including the formation of dental structures, is a complex
and delicate process guided by specific genetic programs. Genetic changes and …

MicroRNA-92a upholds Bmp signaling by targeting noggin3 during pharyngeal cartilage formation

G Ning, X Liu, M Dai, A Meng, Q Wang - Developmental cell, 2013 - cell.com
Craniofacial malformations are common structural birth defects and usually associate with
abnormal development of pharyngeal arches. Although some microRNAs have been found …

Studies with Wnt genes and nonsyndromic cleft lip and palate

R Menezes, A Letra, AH Kim… - … Research Part A …, 2010 - Wiley Online Library
BACKGROUND Clefts of the lip and/or palate (cleft lip/palate) are notable for their complex
etiology. The WNT pathway regulates multiple developmental processes including …

The many postures of noncanonical Wnt signaling in development and diseases

Q Xiao, Z Chen, X Jin, R Mao, Z Chen - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Wnt signaling regulates many aspects of vertebrate development. Its dysregulation causes
developmental defects and diseases including cancer. The signaling can be categorized in …

Molecular signaling along the anterior–posterior axis of early palate development

TM Smith, S Lozanoff, PP Iyyanar… - Frontiers in physiology, 2013 - frontiersin.org
Cleft palate is a common congenital birth defect in humans. In mammals, the palatal tissue
can be distinguished into anterior bony hard palate and posterior muscular soft palate that …

Sasa veitchii extracts protect phenytoin-induced cell proliferation inhibition in human lip mesenchymal cells through modulation of miR-27b-5p

Y Tsukiboshi, A Ogata, A Noguchi, Y Mikami… - Biomedical …, 2023 - jstage.jst.go.jp
ABSTRACT A cleft lip, with or without a cleft palate, is a common birth defect caused by
environmental factors or genetic mutations. Environmental factors, such as pharmaceutical …

Altered expression of cell–cell adhesion molecules β-catenin/E-cadherin and related Wnt-signaling pathway in sporadic and syndromal keratocystic odontogenic …

SG Hakim, H Kosmehl, P Sieg, T Trenkle… - Clinical Oral …, 2011 - Springer
Differential diagnosis of the keratocystic odontogenic tumor (KCOT) still represents a
challenging problem especially if compared with the dentigerous cyst, which is similar in …

SHH signaling pathway drives pediatric bone sarcoma progression

F Lézot, I Corre, S Morice, F Rédini, F Verrecchia - Cells, 2020 - mdpi.com
Primary bone tumors can be divided into two classes, benign and malignant. Among the
latter group, osteosarcoma and Ewing sarcoma are the most prevalent malignant primary …

RUNX3, EGR1 and SOX9B form a regulatory cascade required to modulate BMP-signaling during cranial cartilage development in zebrafish

J Dalcq, V Pasque, A Ghaye, A Larbuisson, P Motte… - PLoS one, 2012 - journals.plos.org
The cartilaginous elements forming the pharyngeal arches of the zebrafish derive from
cranial neural crest cells. Their proper differentiation and patterning are regulated by …