Update on atopic dermatitis

T Torres, E Ferreira, M Gonçalo… - Acta medica …, 2019 - repositorio.chporto.pt
With an increasing prevalence during the past decades, atopic dermatitis has become a
global health issue. A literature search following a targeted approach was undertaken to …

The eczema area and severity index—a practical guide

JM Hanifin, W Baghoomian, E Grinich, YA Leshem… - Dermatitis, 2022 - liebertpub.com
Atopic dermatitis is a chronic inflammatory skin condition that affects approximately 18
million people in the United States. Assessing the extent and severity of atopic dermatitis is …

[HTML][HTML] Efficacy and safety of ruxolitinib cream for the treatment of atopic dermatitis: results from 2 phase 3, randomized, double-blind studies

K Papp, JC Szepietowski, L Kircik, D Toth… - Journal of the American …, 2021 - Elsevier
Background Ruxolitinib (RUX) cream demonstrated potent anti-inflammatory and antipruritic
efficacy in a phase 2 study in adults with atopic dermatitis (AD). Objective To evaluate 8 …

Trial of nemolizumab and topical agents for atopic dermatitis with pruritus

K Kabashima, T Matsumura, H Komazaki… - … England Journal of …, 2020 - Mass Medical Soc
Background Nemolizumab is a subcutaneously administered humanized monoclonal
antibody against interleukin-31 receptor A, which is involved in pruritus and inflammation in …

JAK inhibitors for atopic dermatitis: an update

H He, E Guttman-Yassky - American journal of clinical dermatology, 2019 - Springer
Atopic dermatitis (AD) is one of the most common inflammatory skin diseases. AD is driven
by barrier dysfunction and abnormal immune activation of T helper (Th) 2, Th22, and varying …

Bleach baths for atopic dermatitis: A systematic review and meta-analysis including unpublished data, Bayesian interpretation, and GRADE

L Bakaa, JM Pernica, RJ Couban, KJ Tackett… - Annals of Allergy …, 2022 - Elsevier
Background Bleach bathing is frequently recommended to treat atopic dermatitis (AD), but its
efficacy and safety are uncertain. Objective To systematically synthesize randomized …

Stratum corneum lipid and cytokine biomarkers at age 2 months predict the future onset of atopic dermatitis

E Berdyshev, J Kim, BE Kim, E Goleva… - Journal of Allergy and …, 2023 - Elsevier
Background Atopic dermatitis (AD) commonly occurs in children and can progress into
severe phenotypes or atopic march, causing significant impairment in quality of life. It is …

[HTML][HTML] Probiotics in the therapeutic arsenal of dermatologists

V Navarro-López, E Núñez-Delegido, B Ruzafa-Costas… - Microorganisms, 2021 - mdpi.com
During the last years, numerous studies have described the presence of significant gut and
skin dysbiosis in some dermatological diseases such as atopic dermatitis, psoriasis and …

Emerging role of janus kinase inhibitors for the treatment of atopic dermatitis

R Singh, CE Heron, RI Ghamrawi… - ImmunoTargets and …, 2020 - Taylor & Francis
Background Atopic dermatitis (AD) is a common chronic, inflammatory skin condition. The
pathogenesis of AD involves many cytokines that utilize the Janus kinase/signal transducer …

Assessing the severity of atopic dermatitis in clinical trials and practice

R Chopra, JI Silverberg - Clinics in Dermatology, 2018 - Elsevier
There is a tremendous need for accurate and reproducible scoring systems for the grading
of skin disease to further the development of research and standards of care. There are …