Increasingly vitamin D deficiency is being associated with a number of psychiatric
conditions. In particular for disorders with a developmental basis, such as autistic spectrum …

Midbrain dopaminergic (mDA) neuron development has been an intense area of research
during recent years. This is due in part to a growing interest in regenerative medicine and …

Posttranslational modifications of histone N-terminal tails impact chromatin structure and
gene transcription. While the extent of histone acetylation is determined by both …

Abstract 1, 25 (OH) 2 D 3 (vitamin D) is well-recognized as a neurosteroid that modulates
multiple brain functions. A growing body of evidence indicates that vitamin D plays a pivotal …

Activation of microglia and inflammation-mediated neurotoxicity are suggested to play a
decisive role in the pathogenesis of several neurodegenerative disorders. Activated …

The mechanism by which adult neural stem cells (NSCs) are established during
development is unclear. In this study, analysis of cell cycle progression by examining …

The NR superfamily comprises 48 transcription factors in humans that control a plethora of
gene network programs involved in a wide range of physiologic processes. This review will …

Vitamin D deficiency is prevalent throughout the world, and growing evidence supports a
requirement for optimal vitamin D levels for the healthy developing and adult brain. Vitamin …

In Parkinson disease (PD), affected midbrain dopamine (DA) neurons lose specific
dopaminergic properties before the neurons die. How the phenotype of DA neurons is …

It has been 20 years since we first proposed vitamin D as a “possible” neurosteroid.(1) Our
work over the last two decades, particularly results from our cellular and animal models, has …