Association Between Baseline Driving Pressure and Mortality in Very Old Patients with Acute Respiratory Distress Syndrome

E Papoutsi, K Gkirgkiris, V Tsolaki… - American Journal of …, 2024 - atsjournals.org
Rationale: Because of the effects of aging on the respiratory system, it is conceivable that the
association between driving pressure and mortality depends on age. Objectives: We …

[HTML][HTML] Association between ventilatory ratio and mortality persists in patients with ARDS requiring prolonged mechanical ventilation

E Papoutsi, VG Giannakoulis, C Routsi… - Intensive Care …, 2023 - Springer
Dear Editor, There is an increasing interest in temporal dynamics of predictors of mortality
among patients with acute respiratory distress syndrome (ARDS)[1]. For example, although …

Racial and ethnic minority participants in clinical trials of acute respiratory distress syndrome

E Papoutsi, P Kremmydas, V Tsolaki, A Kyriakoudi… - Intensive Care …, 2023 - Springer
Purpose There is growing interest in improving the inclusiveness of racial and ethnic
minority participants in trials of acute respiratory distress syndrome (ARDS). With our study …

A combination of mild-moderate hypoxemia and low compliance is highly prevalent in persistent ARDS: a retrospective study

E Papoutsi, I Andrianopoulos, V Mavrikaki, M Bolaki… - Respiratory …, 2024 - Springer
Abstract Background The Acute Respiratory Distress Syndrome (ARDS) is characterized by
lung inflammation and edema, impairing both oxygenation and lung compliance. Recent …

Impacts of initial ICU driving pressure on outcomes in acute hypoxemic respiratory failure: a MIMIC-IV database study

CM Xie, WY Tang, JY Leng, P Yang, Y Zhang… - Scientific Reports, 2024 - nature.com
Driving pressure (DP) is a marker of severity of lung injury in patients with acute respiratory
distress syndrome (ARDS) and has a strong association with outcome. However, it is …

[HTML][HTML] Virtual patient with temporal evolution for mechanical ventilation trial studies: A stochastic model approach

CYS Ang, YS Chiew, X Wang, EH Ooi, MBM Nor… - Computer Methods and …, 2023 - Elsevier
Background and objective Healthcare datasets are plagued by issues of data scarcity and
class imbalance. Clinically validated virtual patient (VP) models can provide accurate in …

Prolonged mechanical ventilation in acute respiratory distress syndrome

I Andrianopoulos, VG Giannakoulis, E Papoutsi… - Shock, 2023 - journals.lww.com
Purpose Trajectory of acute respiratory distress syndrome (ARDS) spans from rapidly
improving cases to cases receiving prolonged mechanical ventilation (PMV). We attempted …

Driving Pressure: What Is the Harm?

JE Millar, DF McAuley, JJ Marini - Critical Care Medicine, 2023 - journals.lww.com
Mechanical ventilation is simultaneously a lifesaving intervention and the driver of ventilator-
induced lung injury (VILI). Although we have devoted considerable effort to understand and …

[PDF][PDF] Drug-overdose associated acute hypoxemic respiratory failure: A secondary analysis.

K Gkirgkiris, E Papoutsi, N Athanasiou, S Gκoufas… - Pneumon, 2024 - hts.org.gr
ABSTRACT INTRODUCTION The majority of fatal drug overdose cases are due to acute
hypoxemic respiratory failure (AHRF). We examined whether AHRF associated with drug …