Damage mechanisms to oligodendrocytes and white matter in central nervous system injury: the Australian context

A Warnock, LM Toomey, AJ Wright, K Fisher… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) and spinal cord injury (SCI) present a significant contribution to
the global disease burden. White matter tracts are susceptible to both the physical forces of …

Diffusion tensor imaging and plasma immunological biomarker panel in a rat traumatic brain injury (TBI) model and in human clinical TBI

XV To, AZ Mohamed, P Cumming… - Frontiers in …, 2024 - frontiersin.org
Introduction Neuroinflammatory reactions play a significant role in the pathology and long-
term consequences of traumatic brain injury (TBI) and may mediate salutogenic processes …

Traumatic brain injury augurs ill for prolonged deficits in the brain's structural and functional integrity following controlled cortical impact injury

AZ Mohamed, P Cumming, FA Nasrallah - Scientific reports, 2021 - nature.com
Previous neuroimaging studies in rodents investigated effects of the controlled cortical
impact (CCI) model of traumatic brain injury (TBI) within one-month post-TBI. This study …

Effect of low intensity transcranial ultrasound (LITUS) on post-traumatic brain edema in Rats: evaluation by isotropic 3-dimensional T2 and multi-TE T2 weighted MRI

T Zheng, J Du, Y Yuan, S Wu, Y Jin, Q Shi… - Frontiers in …, 2020 - frontiersin.org
Background: Brain edema is one of the important factors affecting the prognosis of traumatic
brain injury (TBI). Low-intensity transcranial ultrasound (LITUS) has significant anti-cerebral …

Escalation of tau accumulation after a traumatic brain injury: findings from positron emission tomography

AZ Mohamed, P Cumming, FA Nasrallah… - Brain Sciences, 2022 - mdpi.com
Traumatic brain injury (TBI) has come to be recognized as a risk factor for Alzheimer's
disease (AD), with poorly understood underlying mechanisms. We hypothesized that a …

Subacute cytokine changes after a traumatic brain injury predict chronic brain microstructural alterations on advanced diffusion imaging in the male rat

XV To, AZ Mohamed, P Cumming… - Brain, behavior, and …, 2022 - Elsevier
Introduction The process of neuroinflammation occurring after traumatic brain injury (TBI)
has received significant attention as a potential prognostic indicator and interventional target …

Diffusion tensor imaging-based studies at the group-level applied to animal models of neurodegenerative diseases

HP Müller, F Roselli, V Rasche… - Frontiers in neuroscience, 2020 - frontiersin.org
The understanding of human and non-human microstructural brain alterations in the course
of neurodegenerative diseases has substantially improved by the non-invasive magnetic …

Blockade of TRPC channels limits cholinergic-driven hyperexcitability and seizure susceptibility after traumatic brain injury

CM Carver, HR DeWitt, AP Stoja… - Frontiers in …, 2021 - frontiersin.org
We investigated the contribution of excitatory transient receptor potential canonical (TRPC)
cation channels to posttraumatic hyperexcitability in the brain 7 days following controlled …

Combined diffusion tensor imaging and quantitative susceptibility mapping discern discrete facets of white matter pathology post-injury in the rodent brain

N Soni, V Vegh, XV To, AZ Mohamed, K Borges… - Frontiers in …, 2020 - frontiersin.org
Early loss of white matter microstructure integrity is a significant cause of long-term
neurological disorders following traumatic brain injury (TBI). White matter abnormalities …

Diffusion tensor imaging detects acute pathology-specific changes in the P301L tauopathy mouse model following traumatic brain injury

N Soni, R Medeiros, K Alateeq, XV To… - Frontiers in …, 2021 - frontiersin.org
Traumatic brain injury (TBI) has been linked with tauopathy. However, imaging methods that
can non-invasively detect tau-protein abnormalities following TBI need further investigation …