Current status of skin cancers with a focus on immunology and immunotherapy

M Khayyati Kohnehshahri, A Sarkesh… - Cancer Cell …, 2023 - Springer
Skin cancer is one of the most widespread cancers, with a significant global health effect. UV-
induced DNA damage in skin cells triggers them to grow and proliferate out of control …

Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma

DA Mitchell, W Xie, R Schmittling, C Learn… - Neuro …, 2008 - academic.oup.com
Human cytomegalovirus (HCMV) has been described to be associated with several human
malignancies, though the frequency of detection remains controversial. It is unclear whether …

Detection of human cytomegalovirus in normal and neoplastic breast epithelium

LE Harkins, LA Matlaf, L Soroceanu, K Klemm, WJ Britt… - Herpesviridae, 2010 - Springer
Introduction Human cytomegalovirus (HCMV) establishes a persistent life-long infection, and
can cause severe pathology in the fetus and the immunocompromised host [1]. Breast milk is …

Oncomodulatory mechanisms of human cytomegalovirus in gliomas

K Barami - Journal of Clinical Neuroscience, 2010 - Elsevier
Human cytomegalovirus (HCMV), a widespread beta-herpes virus, infects a high percentage
of high grade gliomas. Although HCMV is not recognized as an oncogenic virus, it might …

HCMV activates the IL-6-JAK-STAT3 axis in HepG2 cells and primary human hepatocytes

Q Lepiller, W Abbas, A Kumar, MK Tripathy, G Herbein - PloS one, 2013 - journals.plos.org
Objectives There has been increased interest in the possible role of human cytomegalovirus
(HCMV) in carcinogenesis during the last decade. HCMV seroprevalence was enhanced in …

Human cytomegalovirus tegument protein pp65 is detected in all intra-and extra-axial brain tumours independent of the tumour type or grade

S Libard, SN Popova, RM Amini, V Kärjä, T Pietiläinen… - PloS one, 2014 - journals.plos.org
Human cytomegalovirus (HCMV) has been indicated being a significant oncomodulator.
Recent reports have suggested that an antiviral treatment alters the outcome of a …

CD8+ immunosenescence predicts post-transplant cutaneous squamous cell carcinoma in high-risk patients

MJ Bottomley, PN Harden, KJ Wood - Journal of the American …, 2016 - journals.lww.com
Most morbidity associated with malignancy in long-term renal transplant recipients is due to
cutaneous squamous cell carcinoma (SCC). Previously identified measures to stratify SCC …

Viral DNA detection and RAS mutations in actinic keratosis and nonmelanoma skin cancers

A Zaravinos, P Kanellou… - British Journal of …, 2010 - academic.oup.com
Background Actinic keratosis (AK) is a well‐established precancerous skin lesion that has
the potential to progress to squamous cell carcinoma (SCC). Basal cell carcinoma (BCC) is …

Cytomegalovirus pp71 protein is expressed in human glioblastoma and promotes pro-angiogenic signaling by activation of stem cell factor

LA Matlaf, LE Harkins, V Bezrookove, CS Cobbs… - PloS one, 2013 - journals.plos.org
Glioblastoma multiforme (GBM) is a highly malignant primary central nervous system
neoplasm characterized by tumor cell invasion, robust angiogenesis, and a mean survival of …

High prevalence of HCMV and viral load in tumor tissues and peripheral blood of glioblastoma multiforme patients

CJ dos Santos, LM Stangherlin… - Journal of medical …, 2014 - Wiley Online Library
Glioblastoma multiforme is the most prevalent and malignant tumor of the central nervous
system. In the last few years, accumulating evidence has suggested an association between …