Hyperpolarized water as universal sensitivity booster in biomolecular NMR
NMR spectroscopy is the only method to access the structural dynamics of biomolecules at
high (atomistic) resolution in their native solution state. However, this method's low …
high (atomistic) resolution in their native solution state. However, this method's low …
13C Direct Detected NMR for Challenging Systems
IC Felli, R Pierattelli - Chemical Reviews, 2022 - ACS Publications
Thanks to recent improvements in NMR spectrometer hardware and pulse sequence design,
modern 13C NMR has become a useful tool for biomolecular applications. The complete …
modern 13C NMR has become a useful tool for biomolecular applications. The complete …
[HTML][HTML] Ultrafast 2D NMR for the analysis of complex mixtures
C Lhoste, B Lorandel, C Praud, A Marchand… - Progress in Nuclear …, 2022 - Elsevier
Abstract 2D NMR is extensively used in many different fields, and its potential for the study of
complex biochemical or chemical mixtures has been widely demonstrated. 2D NMR gives …
complex biochemical or chemical mixtures has been widely demonstrated. 2D NMR gives …
[HTML][HTML] Room-temperature dynamic nuclear polarization enhanced NMR spectroscopy of small biological molecules in water
Nuclear magnetic resonance (NMR) spectroscopy is a powerful and popular technique for
probing the molecular structures, dynamics and chemical properties. However the …
probing the molecular structures, dynamics and chemical properties. However the …
Frémy's salt as a low-persistence hyperpolarization agent: efficient dynamic nuclear polarization plus rapid radical scavenging
M Negroni, E Turhan, T Kress, M Ceillier… - Journal of the …, 2022 - ACS Publications
Nuclear magnetic resonance (NMR) spectroscopy is a key technique for molecular structure
determination in solution. However, due to its low sensitivity, many efforts have been made …
determination in solution. However, due to its low sensitivity, many efforts have been made …
Toward protein NMR at physiological concentrations by hyperpolarized water—Finding and mapping uncharted conformational spaces
Nuclear magnetic resonance (NMR) spectroscopy is a key method for determining the
structural dynamics of proteins in their native solution state. However, the low sensitivity of …
structural dynamics of proteins in their native solution state. However, the low sensitivity of …
Glycan Shape, Motions, and Interactions Explored by NMR Spectroscopy
G Widmalm - JACS Au, 2024 - ACS Publications
Glycans in the form of oligosaccharides, polysaccharides, and glycoconjugates are
ubiquitous in nature, and their structures range from linear assemblies to highly branched …
ubiquitous in nature, and their structures range from linear assemblies to highly branched …
Inversion of Hyperpolarized 13C NMR Signals through Cross-Correlated Cross-Relaxation in Dissolution DNP Experiments
Dissolution dynamic nuclear polarization (DDNP) is a versatile tool to boost signal
amplitudes in solution-state nuclear magnetic resonance (NMR) spectroscopy. For DDNP …
amplitudes in solution-state nuclear magnetic resonance (NMR) spectroscopy. For DDNP …
[HTML][HTML] Nuclear Overhauser spectroscopy in hyperpolarized water–chemical vs. magnetic exchange
Dissolution dynamic nuclear polarization (dDNP) is a versatile hyperpolarization technique
to boost signal intensities in nuclear magnetic resonance (NMR) spectroscopy. The …
to boost signal intensities in nuclear magnetic resonance (NMR) spectroscopy. The …
[HTML][HTML] Residue-resolved monitoring of protein hyperpolarization at sub-second time resolution
M Negroni, D Kurzbach - Communications Chemistry, 2021 - nature.com
Signal-enhancement techniques for NMR spectroscopy are important to amplify the weak
resonances provided by nuclear spins. Recently,'hyperpolarization'techniques have been …
resonances provided by nuclear spins. Recently,'hyperpolarization'techniques have been …