Functional implications of single nucleotide polymorphisms (SNPs) in protein-coding and non-coding RNA genes in multifactorial diseases

J Ramírez-Bello, M Jiménez-Morales - Gaceta medica de Mexico, 2017 - medigraphic.com
Single nucleotide polymorphisms (SNPs) represent the most common type of variation in the
human genome. The SNPs located in protein-coding and non-coding RNA genes are …

Altered expression of long non-coding RNA GAS5 in digestive tumors

S Lu, Z Su, W Fu, Z Cui, X Jiang, S Tai - Bioscience Reports, 2019 - portlandpress.com
Cancer has become one of the most important diseases that affect human health and life.
The effects of cancer in the digestive system are particularly prominent. Recently, long non …

[HTML][HTML] Host single nucleotide polymorphisms modulating influenza A virus disease in humans

A Nogales, M L. DeDiego - Pathogens, 2019 - mdpi.com
A large number of human genes associated with viral infections contain single nucleotide
polymorphisms (SNPs), which represent a genetic variation caused by the change of a …

[PDF][PDF] Implicaciones funcionales de los polimorfismos de un solo nucleótido (SNP) en genes codificantes de proteínas y no codificantes en enfermedades …

J Ramírez-Bello, M Jiménez-Morales - Gac Med Mex, 2017 - anmm.org.mx
Los SNP representan las variantes genéticas más comunes del genoma humano. Estas
alteraciones de un solo nucleótido, localizadas tanto en genes codificantes como en no …

[HTML][HTML] Association between tumor necrosis factor-alpha G-308A polymorphism and dental peri-implant disease risk: A meta-analysis

YY Mo, XT Zeng, H Weng, Y Cen, Q Zhao, X Wen - Medicine, 2016 - journals.lww.com
Background: Tumor necrosis factor-alpha (TNF-α) is a potent immune-inflammatory mediator
involved in the regulation of bone resorption. The single nucleotide polymorphism G-308A in …

El factor de necrosis tumoral α (TNF-α) en las enfermedades autoinmunes (EA): biología molecular y genética

JM Fragoso, GV Alarcón, SJ Morales… - Gaceta Médica de …, 2014 - medigraphic.com
It has been estimated that autoimmune diseases (AIDs) affect 5-8% of the US population.
AIDs are a serious public health problem worldwide. These diseases are chronic conditions …

Association of the− 1031 T> C polymorphism and soluble TNF-α levels with Acute Coronary Syndrome

E Sandoval-Pinto, JR Padilla-Gutiérrez… - Cytokine, 2016 - Elsevier
Introduction Inflammation has gained a pivotal role in the pathophysiology of Acute
Coronary Syndrome (ACS). TNF-α is a pro-inflammatory cytokine that could be a potential …

Genetics and genomics in rheumatoid arthritis (RA): an update

AK Rodríguez-Elías, K Maldonado-Murillo… - Gaceta medica de …, 2016 - medigraphic.com
Rheumatoid arthritis is a chronic inflammatory autoimmune disease that affects
approximately 0.5-1% of the general population and leads to chronic synovial inflammation …

[PDF][PDF] Genética y genómica en artritis reumatoide (AR): una actualización

AK Rodríguez-Elías, K Maldonado-Murillo… - Gaceta médica de …, 2016 - anmm.org.mx
La AR, una enfermedad inflamatoria, crónica y autoinmune, afecta aproximadamente al 1%
de la población general. Se caracteriza por presentar inflamación, dolor, destrucción del …

[HTML][HTML] Эволюционно-генетический анализ роли регуляторных участков гена CORO2A в формировании наследственной предрасположенности к …

ВН Сереброва, ЕА Трифонова… - Научные результаты …, 2018 - cyberleninka.ru
Актуальность: Преэклампсия (ПЭ) признана одним из наиболее тяжелых осложнений
беременности и является ведущей причиной материнской и перинатальной …