Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor and the
sixth most common cancer worldwide. Current treatment strategies for HNSCC are surgery …

Esophageal cancer (EC) has been a leading cause of cancer death worldwide in part due to
late detection and lack of precision treatment. EC includes two major malignancies …

Esophageal cancer is one of the most lethal cancers worldwide with poor survival and
limited therapeutic options. The discovery of microRNAs created a new milestone in cancer …

Abstract Tumor-initiating cells (TIC), also known as cancer stem cells, are regarded widely
as a specific subpopulation of cells needed for cancer initiation and progression. TICs have …

Human pluripotent embryonic stem cells have two special features: self-renewal and
pluripotency. It is important to understand the properties of pluripotent stem cells and …

Gastrointestinal (GI) cancers are among the main reasons for cancer death globally. The
deadliest types of GI cancer include colon, stomach, and liver cancers. Multiple lines of …

Esophageal squamous cell carcinoma (ESCC) is a very common malignant tumor with poor
prognosis in China. Chemokines secreted by tumors are pivotal for the accumulation of …

ABCG2 is one of at least three human ATP binding cassette (ABC) transporters which can
facilitate the export from cells of a wide range of chemically unrelated drug molecules. This …

Cancer stem cells (CSCs) or tumor-initiating cells (TICs), a small subset of tumor cells, are
involved in tumor initiation, progression, recurrence and metastasis. In human …

Head and neck squamous cell carcinoma (HNSCC) is currently one of the 10 most common
malignancies worldwide, characterized by a biologically highly diverse group of tumors with …