Obesity, inflammation, and cancer

T Deng, CJ Lyon, S Bergin, MA Caligiuri… - Annual Review of …, 2016 - annualreviews.org
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including cancer, and is increasingly recognized as a growing cause of preventable cancer …

[HTML][HTML] From conventional to precision therapy in canine mammary cancer: a comprehensive review

G Valdivia, Á Alonso-Diez, D Pérez-Alenza… - Frontiers in veterinary …, 2021 - frontiersin.org
Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …

[HTML][HTML] Mechanisms linking obesity to male infertility

A Katib - Central European journal of urology, 2015 - ncbi.nlm.nih.gov
Results Among the myriad of publications reviewed in this paper, impaired spermatogenesis
and sexual dysfunction have been shown to drive other variables towards poor fertility …

[HTML][HTML] Obesity as a premature aging phenotype—implications for sarcopenic obesity

E Nunan, CL Wright, OA Semola, M Subramanian… - Geroscience, 2022 - Springer
Obesity and aging have both seen dramatic increases in prevalence throughout society.
This review seeks to highlight common pathologies that present with obesity, along with the …

Effects of nano-encapsulated curcumin-chrysin on telomerase, MMPs and TIMPs gene expression in mouse B16F10 melanoma tumour model

F Tavakoli, R Jahanban-Esfahlan, K Seidi… - Artificial cells …, 2018 - Taylor & Francis
Due to the high rate of drug resistance among malignant melanoma cases, it seems
necessary to introduce an efficient pharmaceutical approach to melanoma treatment. For …

[HTML][HTML] Obesity, metabolism and the microenvironment: Links to cancer

S Sundaram, AR Johnson, L Makowski - Journal of carcinogenesis, 2013 - ncbi.nlm.nih.gov
Historically, cancer research has focused on identifying mutations or amplification of genes
within the tumor, which informed the development of targeted therapies against affected …

[HTML][HTML] Uterine fibroids—Causes, impact, treatment, and lens to the African perspective

N Sefah, S Ndebele, L Prince, E Korasare… - Frontiers in …, 2023 - frontiersin.org
Leiomyomas, or uterine fibroids as they are commonly known, are mostly seen in women of
reproductive age. However, they can go undetected in most women, and approximately 25 …

Implications of resistin in type 2 diabetes mellitus and coronary artery disease: Impairing insulin function and inducing pro‐inflammatory cytokines

M Emamalipour, K Seidi… - Journal of cellular …, 2019 - Wiley Online Library
Diabetes mellitus is a metabolic and chronic disorder, which is very common all over the
world. Many genetic and nongenetic factors are involved in the development of type 2 …

The inhibitory effects of nano-encapsulated metformin on growth and hTERT expression in breast cancer cells

S Javidfar, Y Pilehvar-Soltanahmadi… - Journal of drug delivery …, 2018 - Elsevier
Metformin has recently received attention for its potential effects with respect to cancer
prevention and treatment. Nonetheless, the low bioavailability and short half-life of …

[HTML][HTML] Genistein inhibits the proliferation and differentiation of MCF-7 and 3T3-L1 cells via the regulation of ERα expression and induction of apoptosis

EJ Choi, JY Jung, GH Kim - Experimental and …, 2014 - spandidos-publications.com
The present study investigated the effect of the phytochemical genistein on the proliferation
and differentiation of MCF-7 and 3T3-L1 cells via the regulation of estrogen receptor-α (ERα) …