Current strategies against COVID-19

S Hussain, YJ Xie, D Li, SI Malik, J Hou, ELH Leung… - Chinese Medicine, 2020 - Springer
Abstract Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) recently was declared a pandemic by world health …

[HTML][HTML] CD163+ tumor-associated macrophage is a prognostic biomarker and is associated with therapeutic effect on malignant pleural effusion of lung cancer …

L Yang, F Wang, L Wang, L Huang, J Wang, B Zhang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Abstract CD163+ tumor-associated macrophages (TAMs) play an important role in the
progression of cancer. However, the significance of CD163+ TAMs in malignant pleural …

Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells

J Liu, J Gu, Z Feng, Y Yang, N Zhu, W Lu… - Journal of translational …, 2016 - Springer
Background Histone deacetylase (HDAC) inhibitors are widely used in clinical investigation
as novel drug targets. For example, panobinostat and vorinostat have been used to treat …

Trends in Anti-Tumor Effects of Pseudomonas aeruginosa Mannose-Sensitive-Hemagglutinin (PA-MSHA): An Overview of Positive and Negative Effects

D Bozic, J Živanović, K Živančević, K Baralić… - Cancers, 2024 - mdpi.com
Simple Summary Finding the best treatment for cancer remains one of the biggest scientific
challenges in the 21st century. Available cancer treatments have issues like drug resistance …

Cholera toxin B subunit acts as a potent systemic adjuvant for HIV-1 DNA vaccination intramuscularly in mice

J Hou, Y Liu, J Hsi, H Wang, R Tao… - Human vaccines & …, 2014 - Taylor & Francis
Cholera toxin B subunit (CTB) was investigated as a classical mucosal adjuvant that can
increase vaccine immunogenicity. In this study, we found out the in vitro efficacy of cholera …

Mannose‐mediated inhibitory effects of PA‐MSHA on invasion and metastasis of hepatocellular carcinoma via EGFR/Akt/IκBβ/NF‐κB pathway

T Li, ZR Dong, ZY Guo, CH Wang, XT Zhi… - Liver …, 2015 - Wiley Online Library
Abstract Background & Aims Elevation of high‐mannose glycans is a common feature of
malignant cells and has been suggested to be the basis for alternative cancer therapy for …

Pseudomonas aeruginosa Mannose-Sensitive Hemagglutinin Promotes T-Cell Response via Toll-Like Receptor 4–Mediated Dendritic Cells to Slow Tumor …

M Zhang, F Luo, Y Zhang, L Wang, W Lin… - … of Pharmacology and …, 2014 - ASPET
Pseudomonas aeruginosa–mannose-sensitive hemagglutinin (PA-MSHA) as a drug may kill
tumor cells and has been used clinically. However, the antitumor immune response of PA …

Pseudomonas aeruginosa-mannose sensitive hemagglutinin injection treated cytokine-induced killer cells combined with chemotherapy in the treatment of …

C Zhang, Z Zhang, L Wang, J Han, F Li, C Shen… - International …, 2017 - Elsevier
Pseudomonas aeruginosa-mannose sensitive hemagglutinin (PA-MSHA) injection serves
as immunological adjuvant in clinical treatment of cancer patients. In present study, we …

The MSHA strain of Pseudomonas aeruginosa (PA-MSHA) inhibits gastric carcinoma progression by inducing M1 macrophage polarization

C Wang, Z Hu, Z Zhu, X Zhang, Z Wei, Y Zhang, D Hu… - Tumor Biology, 2016 - Springer
Macrophages play crucial roles in promoting tumor development and progression. In the
present study, we found that the mannose-sensitive hemagglutination pilus strain of …

[HTML][HTML] Neoadjuvant Pseudomonas aeruginosa mannose-sensitive hemagglutinin (PA-MSHA) and chemotherapy versus placebo plus chemotherapy in patients with …

Y Gong, H Zuo, Y Zhou, KD Yu, GY Liu… - Annals of …, 2023 - ncbi.nlm.nih.gov
Background According to preclinical experiments, Pseudomonas aeruginosa mannose-
sensitive hemagglutinin (PA-MSHA) exerts antiproliferative effects against breast cancer …