The potential for adverse effects in fish exposed to antidepressants in the aquatic environment

SL Gould, MJ Winter, WHJ Norton… - … Science & Technology, 2021 - ACS Publications
Antidepressants are one of the most commonly prescribed pharmaceutical classes for the
treatment of psychiatric conditions. They act via modulation of brain monoaminergic …

A large aerobic scope and complex regulatory abilities confer hypoxia tolerance in larval toadfish, Opsanus beta, across a wide thermal range

LA Frank, J Serafy, M Grosell - Science of The Total Environment, 2023 - Elsevier
Few studies have been performed on early-life stage toadfish, and none have addressed
their tolerance to temperature and hypoxia despite large seasonal temperature fluctuations …

Exposure to wastewater effluent disrupts hypoxia responses in killifish (Fundulus heteroclitus)

SC Lau, H Mehdi, LM Bragg, MR Servos… - Environmental …, 2021 - Elsevier
Hypoxia (low oxygen) often occurs in aquatic ecosystems that receive effluent from
municipal wastewater treatment plants (WWTP). The combination of hypoxia and WWTP …

Molecular and functional characterization of the Gulf toadfish serotonin transporter SLC6A4

MHB Amador, MD McDonald - Journal of Experimental …, 2018 - journals.biologists.com
The serotonin transporter (SERT) functions in the uptake of the neurotransmitter serotonin (5-
HT) from the extracellular milieu and is the molecular target of the selective serotonin re …

Mild hypoxia exposure impacts peripheral serotonin uptake and degradation in Gulf toadfish (Opsanus beta)

J Sebastiani, A Sabatelli… - Journal of Experimental …, 2022 - journals.biologists.com
ABSTRACT Plasma serotonin (5-hydroxytryptamine, 5-HT) homeostasis is maintained
through the combined processes of uptake (via the 5-HT transporter SERT, and others) …

Gulf toadfish (Opsanus beta) gill neuroepithelial cells in response to hypoxia exposure

OA Duh, MD McDonald - Journal of Comparative Physiology B, 2024 - Springer
Neuroepithelial cells (NECs) within the fish gill contain the monoamine neurochemical
serotonin (5-HT), sense changes in the partial pressure of oxygen (PO 2) in the surrounding …

Is serotonin uptake by peripheral tissues sensitive to hypoxia exposure?

MHB Amador, MD McDonald - Fish physiology and biochemistry, 2022 - Springer
Abstract In the Gulf toadfish (Opsanus beta), the serotonin (5-HT) transporter (SERT) is
highly expressed in the heart, and the heart and gill both demonstrate the capacity for SERT …

The effect of normoxia exposure on hypoxia tolerance and sensory sampling in a swamp-dwelling mormyrid fish

SB Clarke, LJ Chapman, R Krahe - … and Physiology Part A: Molecular & …, 2020 - Elsevier
Abstract Effects of energetic limitations on the performance of sensory systems are generally
difficult to quantify. Weakly electric fishes provide an ideal model system to quantify the …

The serotonin transporter and nonselective transporters are involved in peripheral serotonin uptake in the Gulf toadfish, Opsanus beta

MHB Amador, MD McDonald - American Journal of …, 2018 - journals.physiology.org
In mammals, circulating serotonin [5-hydroxytryptamine (5-HT)] is sequestered by platelets
via the 5-HT transporter (SERT) to prevent unintended signaling by this potent signaling …

Biological effects of antidepressants on marine organisms

AL Maulvault, I Marmelo, P Anacleto… - Pharmaceuticals in Marine …, 2021 - Elsevier
Antidepressants are increasingly more prescribed and chronically consumed, particularly in
developed countries. Water bodies are often the final destination of pollutants discharged …