The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Personalized medicine refers to the tailored application of medical treatment at an individual
level, considering the specific genotype or phenotype of each patient for targeted therapy. In …

Significance All-optical cardiac electrophysiology enables the visualization and control of
key parameters relevant to the detection of cardiac arrhythmias. Mapping such responses in …

The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Cardiac arrhythmia treatment is a clinical challenge necessitating safer and more effective
therapies. Recent studies have highlighted the role of the perinexus, an intercalated disc …

Current understanding of arrhythmia mechanisms and design of anti-arrhythmic drug
therapies hinges on the assumption that myocytes from the same region of a single heart …

The key areas of application of systems with microelectrode arrays (MEA) are studying the
mechanisms of diseases and testing the effect of drugs on the human body using “laboratory …

Scalable and high-throughput electrophysiological measurement systems are necessary to
accelerate the elucidation of cardiac diseases in drug development. Optical mapping is the …

The high prevalence and poor prognosis of heart failure are two key drivers for research into
cardiac electrophysiology and regeneration. Dyssynchrony in calcium release and loss of …

Background: Arrhythmogenic Cardiomyopathy (AC) is a genetic cardiac disease resulting
from different mutations within proteins constituting the intercalated disc, including …