Tumour necrosis factor gene polymorphism and disease prevalence

T Qidwai, F Khan - Scandinavian journal of immunology, 2011 - Wiley Online Library
Tumour necrosis factor (TNF), an important proinflammatory cytokine, plays a role in the
regulation of cell differentiation, proliferation and death, as well as in inflammation, innate …

An understanding of the genetic basis of asthma

M Bijanzadeh, PA Mahesh… - Indian Journal of …, 2011 - journals.lww.com
Asthma is the most common chronic childhood disease in developed nations and its
prevalence has increased in the world over the last 25 years. It is a complex disease with …

Quantitative and causal analysis for inflammatory genes and the risk of Parkinson's disease

M Yi, J Li, S Jian, B Li, Z Huang, L Shu… - Frontiers in …, 2023 - frontiersin.org
Background The dysfunction of immune system and inflammation contribute to the
Parkinson's disease (PD) pathogenesis. Cytokines, oxidative stress, neurotoxin and …

Polymorphism of tumor necrosis factor alpha (TNF-alpha) gene promoter, circulating TNF-alpha level, and cardiovascular risk factor for ischemic stroke

G Cui, H Wang, R Li, L Zhang, Z Li, Y Wang… - Journal of …, 2012 - Springer
Background Tumor necrosis factor-α (TNF-α) is one of the most typical pro-inflammatory
cytokines with both beneficial and destructive properties for the central nervous system …

Leprosy as a genetic disease

A Alter, A Grant, L Abel, A Alcaïs, E Schurr - Mammalian genome, 2011 - Springer
Leprosy (Hansen's disease) is a human infectious disease whose etiological agent,
Mycobacterium leprae, was identified by GHA Hansen in the 19th century. Despite the high …

Genetic, immune-inflammatory, and oxidative stress biomarkers as predictors for disability and disease progression in multiple sclerosis

AP Kallaur, EMV Reiche, SR Oliveira, ANC Simão… - Molecular …, 2017 - Springer
The aim of this study was to evaluate the TNFβ Nco I polymorphism (rs909253) and immune-
inflammatory, oxidative, and nitrosative stress (IO&NS) biomarkers as predictors of disease …

Tumor necrosis factor–α is a common genetic risk factor for asthma, juvenile rheumatoid arthritis, and systemic lupus erythematosus in a Mexican pediatric population

S JimÊnez-Morales, R VelÂzquez-Cruz… - Human immunology, 2009 - Elsevier
There is a great deal of evidence that points to the association of the tumor necrosis factor-
alpha (TNF-α) gene as a common genetic factor in the pathogenesis of diseases that are …

Association between genetic variants of IL-1β, IL-6 and TNF-α cytokines and cognitive performance in the elderly general population of the MEMO-study

BT Baune, G Ponath, M Rothermundt, O Riess… - …, 2008 - Elsevier
This study is to investigate the associations between specific polymorphisms in three
cytokine genes and domains of cognitive functioning in a population based study in the …

Lipopolysaccharide (LPS) exposure differently affects allergic asthma exacerbations and its amelioration by intranasal curcumin in mice

A Kumari, D Dash, R Singh - Cytokine, 2015 - Elsevier
Aim Lipopolysaccharide (LPS) is ubiquitous in the environment and can therefore,
exacerbate allergic responses. Studies have suggested immunoregulatory effects of LPS …

Association of TNF‐α with severe respiratory syncytial virus infection and bronchial asthma

B Puthothu, S Bierbaum, MV Kopp… - Pediatric allergy and …, 2009 - Wiley Online Library
Tumor necrosis factor (TNF‐) α is a proinflammatory cytokine that is important in the innate
host defence and thus in the defence of infectious agents. However, in excess it provokes …