The progression of chronic liver diseases (CLD), irrespective of etiology, involves chronic
parenchymal injury, persistent activation of inflammatory response as well as sustained …

Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular
matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic …

Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more
than one million deaths annually via development of cirrhosis, although no antifibrotic …

Reversibility of hepatic fibrosis and cirrhosis following antiviral therapy for hepatitis B or C
has advanced the prospect of developing antifibrotic therapies for patients with chronic liver …

Liver fibrosis is a regenerative process that occurs after injury. It is characterized by the
deposition of connective tissue by specialized fibroblasts and concomitant proliferative …

Summary 16S rRNA-targeted oligonucleotide probes for eubacteria (EUB338), ammonium-
oxidizing bacteria (Nsm156) and nitrite-oxidizing bacteria (Nb1000) were used for the rapid …

Hepatic fibrosis is characterized by the pathological accumulation of extracellular matrix
(ECM) in the liver resulting from the persistent liver injury and wound-healing reaction …

During liver injury, hepatocytes secrete exosomes that include diverse types of self‐RNAs.
Recently, self‐noncoding RNA has been recognized as an activator of Toll‐like receptor 3 …

Nature killer (NK) cells play a critical role in host innate and adaptive immune defense
against viral infections and tumors. NK cells are enriched in liver hematopoietic cells with …

Abstract Growth differentiation factor 15 (GDF15) has recently been shown to have an
important role in the regulation of mitochondrial function and in the pathogenesis of complex …