[HTML][HTML] Current research status of anti-cancer peptides: Mechanism of action, production, and clinical applications

RK Chinnadurai, N Khan, GK Meghwanshi… - Biomedicine & …, 2023 - Elsevier
The escalating rate of cancer cases, together with treatment deficiencies and long-term side
effects of currently used cancer drugs, has made this disease a global burden of the 21st …

Mitochondrial voltage-dependent anion channel 1–hexokinase-II complex-targeted strategy for melanoma inhibition using designed multiblock peptide amphiphiles

F Zhang, A Angelova, VM Garamus… - … Applied Materials & …, 2021 - ACS Publications
Targeted therapies of melanoma are of urgent need considering the resistance of this
aggressive type of cancer to chemotherapeutics. The voltage-dependent anion channel 1 …

Bioactive cationic peptides as potential agents for breast cancer treatment

M Manrique-Moreno, GA Santa-González… - Bioscience …, 2021 - portlandpress.com
Breast cancer continues to affect millions of women worldwide, and the number of new
cases dramatically increases every year. The physiological causes behind the disease are …

Anticancer activity of D-LAK-120A, an antimicrobial peptide, in non-small cell lung cancer (NSCLC)

SM Patil, NK Kunda - Biochimie, 2022 - Elsevier
Non-small cell lung cancer (NSCLC) is a major cause of global cancer mortalities and
accounts for approximately 80–85% of reported lung cancer cases. Conventional …

ΔM4: Membrane-Active Peptide with Antitumoral Potential against Human Skin Cancer Cells

E Fandiño-Devia, GA Santa-González, MC Klaiss-Luna… - Membranes, 2023 - mdpi.com
Peptides have become attractive potential agents due to their affinity to cancer cells. In this
work, the biological activity of the peptide ΔM4 against melanoma cancer cell line A375 …

Cecropin D-derived synthetic peptides in the fight against Candida albicans cell filamentation and biofilm formation

I Guevara-Lora, G Bras, M Juszczak… - Frontiers in …, 2023 - frontiersin.org
The recent progressive increase in the incidence of invasive fungal infections, especially in
immunocompromised patients, makes the search for new therapies crucial in the face of the …

Jellein-I-conjugated gold nanoparticles: Insights into the antibacterial, antibiofilm activities against MRSA, and anticancer properties

A Sattari-Maraji, M Nikchi, M Shahmiri, EM Ahadi… - Journal of Drug Delivery …, 2024 - Elsevier
Antimicrobial peptides (AMPs) and their conjugation with nanoparticles hold promise for
targeting Methicillin-resistant Staphylococcus aureus (MRSA). In this study, Jellein-I peptide …

Comparative Study of the Potential Cell-Penetrating Peptide∆ M4 on Apoptosis Cell Signaling in A375 and A431 Cancer Cell Lines

E Fandiño-Devia, A Brankiewicz, GA Santa-González… - Pharmaceutics, 2024 - mdpi.com
In recent yearsjajajj, peptide-based therapeutics have attracted increasing interest as a
potential approach to cancer treatment. Peptides are characterized by high specificity and …

[HTML][HTML] Assessing the Impact of Green and Roasted Coffee Extracts on Colorectal Cancer Cells in a 3D Cell Culture Model

MD Vélez, GA Santa-González - Phytomedicine Plus, 2024 - Elsevier
Background: Colorectal cancer (CRC) is one of the most common and deadly malignant
neoplasms worldwide. It is associated with multiple lifestyle risk factors such as poor diet …

[HTML][HTML] Investigation of morphological changes of HPS membrane caused by cecropin B through scanning electron microscopy and atomic force microscopy

H Hu, C Jiang, B Zhang, N Guo, Z Li… - Journal of Veterinary …, 2021 - ncbi.nlm.nih.gov
Background Antimicrobial peptides (AMPs) have been identified as promising compounds
for consideration as novel antimicrobial agents. Objectives This study analyzed the efficacy …