Mean platelet volume (MPV): new perspectives for an old marker in the course and prognosis of inflammatory conditions
A Korniluk, OM Koper-Lenkiewicz… - Mediators of …, 2019 - Wiley Online Library
Platelet size has been demonstrated to reflect platelet activity and seems to be a useful
predictive and prognostic biomarker of cardiovascular events. It is associated with a variety …
predictive and prognostic biomarker of cardiovascular events. It is associated with a variety …
Machine learning in cardiovascular medicine: are we there yet?
Artificial intelligence (AI) broadly refers to analytical algorithms that iteratively learn from
data, allowing computers to find hidden insights without being explicitly programmed where …
data, allowing computers to find hidden insights without being explicitly programmed where …
The 'Digital Twin'to enable the vision of precision cardiology
J Corral-Acero, F Margara, M Marciniak… - European heart …, 2020 - academic.oup.com
Providing therapies tailored to each patient is the vision of precision medicine, enabled by
the increasing ability to capture extensive data about individual patients. In this position …
the increasing ability to capture extensive data about individual patients. In this position …
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
In genome-wide association studies (GWAS) for thousands of phenotypes in large biobanks,
most binary traits have substantially fewer cases than controls. Both of the widely used …
most binary traits have substantially fewer cases than controls. Both of the widely used …
Genetic diversity and association studies in US Hispanic/Latino populations: applications in the Hispanic Community Health Study/Study of Latinos
MP Conomos, CA Laurie, AM Stilp, SM Gogarten… - The American Journal of …, 2016 - cell.com
US Hispanic/Latino individuals are diverse in genetic ancestry, culture, and environmental
exposures. Here, we characterized and controlled for this diversity in genome-wide …
exposures. Here, we characterized and controlled for this diversity in genome-wide …
Unravelling the human genome–phenome relationship using phenome-wide association studies
Advances in genotyping technology have, over the past decade, enabled the focused
search for common genetic variation associated with human diseases and traits. With the …
search for common genetic variation associated with human diseases and traits. With the …
New roles for mean platelet volume measurement in the clinical practice?
P Noris, F Melazzini, CL Balduini - Platelets, 2016 - Taylor & Francis
Several hundreds of studies recently investigated mean platelet volume (MPV) as measured
by electronic cell counters in a wide variety of acquired diseases, and most of them found …
by electronic cell counters in a wide variety of acquired diseases, and most of them found …
Predictive modeling of hospital readmission rates using electronic medical record-wide machine learning: a case-study using Mount Sinai heart failure cohort
Reduction of preventable hospital readmissions that result from chronic or acute conditions
like stroke, heart failure, myocardial infarction and pneumonia remains a significant …
like stroke, heart failure, myocardial infarction and pneumonia remains a significant …
Electronic health records-driven phenotyping: challenges, recent advances, and perspectives
With the completion of the Human Genome Project1 as well as recent advances in genomic
science and comparative biological studies, a new era of individualized medicine is evolving …
science and comparative biological studies, a new era of individualized medicine is evolving …
[HTML][HTML] Large and small platelets—(When) do they differ?
S Handtke, T Thiele - Journal of Thrombosis and Haemostasis, 2020 - Elsevier
Platelets are most important in providing cellular hemostasis but also take part in
inflammation and immune processes. Increased platelet size has been regarded as a …
inflammation and immune processes. Increased platelet size has been regarded as a …