[HTML][HTML] Extracellular vesicles: Critical players during cell migration

BH Sung, CA Parent, AM Weaver - Developmental cell, 2021 - cell.com
Cell migration is essential for the development and maintenance of multicellular organisms,
contributing to embryogenesis, wound healing, immune response, and other critical …

Exosomes-regulated lipid metabolism in tumorigenesis and cancer progression

L Ye, Y Li, S Zhang, J Wang, B Lei - Cytokine & Growth Factor Reviews, 2023 - Elsevier
Increasing evidence highlights the role of lipid metabolism in tumorigenesis and tumor
progression. Targeting the processes of lipid metabolism, including lipogenesis, lipid …

Secreted midbody remnants are a class of extracellular vesicles molecularly distinct from exosomes and microparticles

A Rai, DW Greening, R Xu, M Chen… - Communications …, 2021 - nature.com
During the final stages of cell division, newly-formed daughter cells remain connected by a
thin intercellular bridge containing the midbody (MB), a microtubule-rich organelle …

Proteomic profiling of human uterine extracellular vesicles reveal dynamic regulation of key players of embryo implantation and fertility during menstrual cycle

A Rai, QH Poh, M Fatmous, H Fang, S Gurung… - …, 2021 - Wiley Online Library
Endometrial extracellular vesicles (EVs) are emerging as important players in reproductive
biology. However, how their proteome is regulated throughout the menstrual cycle is not …

Intercellular crosstalk between cancer cells and cancer-associated fibroblasts via extracellular vesicles

Y Naito, Y Yoshioka, T Ochiya - Cancer Cell International, 2022 - Springer
Intercellular communication plays an important role in cancer initiation and progression
through direct contact and indirect interactions, such as via secretory molecules. Cancer …

Modeling the role of cancer-associated fibroblasts in tumor cell invasion

S Poon, LE Ailles - Cancers, 2022 - mdpi.com
Simple Summary Accurate in vitro modeling of diseases is essential to making breakthrough
and clinically relevant discoveries. Assays to examine the process of invasion—a classical …

Rapid and in‐depth proteomic profiling of small extracellular vesicles for ultralow samples

J Cross, A Rai, H Fang, B Claridge, DW Greening - Proteomics, 2024 - Wiley Online Library
The integration of robust single‐pot, solid‐phase‐enhanced sample preparation with
powerful liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) is routinely used …

3D cell cultures as prospective models to study extracellular vesicles in cancer

G Bordanaba-Florit, I Madarieta, B Olalde… - Cancers, 2021 - mdpi.com
Simple Summary 3D cell cultures are a qualitative improvement in cancer research because
these models preserve cancer physiological characteristics better than traditional bi …

Proteome reprogramming of endometrial epithelial cells by human trophectodermal small extracellular vesicles reveals key insights into embryo implantation

QH Poh, A Rai, II Carmichael, LA Salamonsen… - …, 2021 - Wiley Online Library
Embryo implantation into the receptive endometrium is critical in pregnancy establishment,
initially requiring reciprocal signalling between outer layer of the blastocyst (trophectoderm …

Extracellular Vesicles: Biological Packages That Modulate Tumor Cell Invasion

M Schmidtmann, C D'Souza-Schorey - Cancers, 2023 - mdpi.com
Simple Summary Cell invasion is an intrinsic cellular behavior wherein cells respond to
various signals and bring about the degradation of the extracellular matrix (ECM) to facilitate …