Peripheral neuropathy is a common complication of a variety of diseases and treatments,
including diabetes, cancer chemotherapy, and infectious causes (HIV, hepatitis C, and …

Background Significant pain from HIV-associated sensory neuropathy (HIV-SN) affects∼
40% of HIV infected individuals treated with antiretroviral therapy (ART). The prevalence of …

There is emerging evidence that people with successfully treated HIV infection age
prematurely, leading to progressive multi-organ disease, but the reasons for this are not …

Management of patients presenting with chronic pain is a common problem in primary care.
Essentially, the classification of chronic pain falls into 3 broad categories:(1) pain owing to …

Background: Combination antiretroviral therapy (cART) has improved the survival of patients
with HIV/AIDS but its impact remains uncertain on the changing prevalence and incidence of …

Findings on the nervous system complications of HIV disease and their impact on people
living with HIV continue to accumulate. New reports at the 17 th Conference on Retroviruses …

Objectives: To estimate neuropathic sign/symptom rates with initiation of combination
antiretroviral therapy (cART) in HIV-infected ART-naive patients, and to investigate risk …

Antiretroviral drugs are associated with a variety of adverse effects on the central and
peripheral nervous systems. The frequency and severity of neuropsychiatric adverse events …

Whilst effective antiretroviral therapy is protective against the more severe forms of HIV-
associated brain disease, there remains a large burden of clinically symptomatic cognitive …

Histone deacetylase inhibitors (HDACIs) interfere with the epigenetic process of histone
acetylation and are known to have analgesic properties in models of chronic inflammatory …