Hydrogels for RNA delivery

R Zhong, S Talebian, BB Mendes, G Wallace… - Nature materials, 2023 - nature.com
RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …

Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Tailored hydrogel delivering niobium carbide boosts ROS‐scavenging and Antimicrobial activities for diabetic wound healing

J Chen, Y Liu, G Cheng, J Guo, S Du, J Qiu, C Wang… - Small, 2022 - Wiley Online Library
The treatment of diabetic wounds remains challenging due to the excess levels of oxidative
stress, vulnerability to bacterial infection, and persistent inflammation response during …

Biomedical applications of hydrogels in drug delivery system: An update

P Kesharwani, A Bisht, A Alexander, V Dave… - Journal of Drug Delivery …, 2021 - Elsevier
Conventional drug delivery system generally deals with the issues involving repeated
dosing and systemic toxicities. Since few decades, hydrogels have played a significant role …

PEG-based thermosensitive and biodegradable hydrogels

J Shi, L Yu, J Ding - Acta biomaterialia, 2021 - Elsevier
Injectable thermosensitive hydrogels are free-flowing polymer solutions at low or room
temperature, making them easy to encapsulate the therapeutic payload or cells via simply …

Review of a new bone tumor therapy strategy based on bifunctional biomaterials

J Liao, R Han, Y Wu, Z Qian - Bone research, 2021 - nature.com
Bone tumors, especially those in osteosarcoma, usually occur in adolescents. The standard
clinical treatment includes chemotherapy, surgical therapy, and radiation therapy …

Recent advances in polymeric micelles for anti-cancer drug delivery

S Biswas, P Kumari, PM Lakhani, B Ghosh - European Journal of …, 2016 - Elsevier
Block co-polymeric micelles receive increased attention due to their ability to load
therapeutics, deliver the cargo to the site of action, improve the pharmacokinetic of the …

Polymer-based nanomaterials and applications for vaccines and drugs

J Han, D Zhao, D Li, X Wang, Z Jin, K Zhao - Polymers, 2018 - mdpi.com
Nanotechnology plays a significant role in drug development. As carriers, polymeric
nanoparticles can deliver vaccine antigens, proteins, and drugs to the desired site of action …

Bioinspired Spatiotemporal Management toward RNA Therapies

Y Ma, S Li, X Lin, Y Chen - ACS nano, 2023 - ACS Publications
Ribonucleic acid (RNA)-based therapies have become an attractive topic in disease
intervention, especially with some that have been approved by the FDA such as the mRNA …

Electroactive composite scaffold with locally expressed osteoinductive factor for synergistic bone repair upon electrical stimulation

L Cui, J Zhang, J Zou, X Yang, H Guo, H Tian, P Zhang… - Biomaterials, 2020 - Elsevier
Tissue engineering is a promising strategy for the repair of large-scale bone defects, in
which scaffolds and growth factors are two critical issues influencing the efficacy of bone …