Using MetaboAnalyst 5.0 for LC–HRMS spectra processing, multi-omics integration and covariate adjustment of global metabolomics data
Liquid chromatography coupled with high-resolution mass spectrometry (LC–HRMS) has
become a workhorse in global metabolomics studies with growing applications across …
become a workhorse in global metabolomics studies with growing applications across …
Advances in decomposing complex metabolite mixtures using substructure-and network-based computational metabolomics approaches
Covering: up to the end of 2020 Recently introduced computational metabolome mining
tools have started to positively impact the chemical and biological interpretation of …
tools have started to positively impact the chemical and biological interpretation of …
OmicsNet 2.0: a web-based platform for multi-omics integration and network visual analytics
Researchers are increasingly seeking to interpret molecular data within a multi-omics
context to gain a more comprehensive picture of their study system. OmicsNet (www …
context to gain a more comprehensive picture of their study system. OmicsNet (www …
Metabolomics and complementary techniques to investigate the plant phytochemical cosmos
Covering: up to 2021 Plants and their associated microbial communities are known to
produce millions of metabolites, a majority of which are still not characterized and are …
produce millions of metabolites, a majority of which are still not characterized and are …
Recent advances in mass spectrometry-based computational metabolomics
The computational metabolomics field brings together computer scientists, bioinformaticians,
chemists, clinicians, and biologists to maximize the impact of metabolomics across a wide …
chemists, clinicians, and biologists to maximize the impact of metabolomics across a wide …
Recent review on selected xenobiotics and their impacts on gut microbiome and metabolome
As it is well known, the gut is one of the primary sites in any host for xenobiotics, and the
many microbial metabolites responsible for the interactions between the gut microbiome and …
many microbial metabolites responsible for the interactions between the gut microbiome and …
Integrated metabolomic–genomic workflows accelerate microbial natural product discovery
The pairing of analytical chemistry with genomic techniques represents a new wave in
natural product chemistry. With an increase in the availability of sequencing and assembly of …
natural product chemistry. With an increase in the availability of sequencing and assembly of …
mGWAS-Explorer 2.0: Causal Analysis and Interpretation of Metabolite–Phenotype Associations
Metabolomics-based genome-wide association studies (mGWAS) are key to understanding
the genetic regulations of metabolites in complex phenotypes. We previously developed …
the genetic regulations of metabolites in complex phenotypes. We previously developed …
Quantitative challenges and their bioinformatic solutions in mass spectrometry-based metabolomics
Improving the quantitative performance of mass spectrometry (MS)-based metabolomics is
the key to its successful application in a broad range of research questions. Like other …
the key to its successful application in a broad range of research questions. Like other …
Software and computational tools for LC-MS-based epilipidomics: Challenges and solutions
Lipids play a crucial role in cellular structure and functions, including cell signaling,
membrane plasticity, and trafficking. Alterations of the lipid composition in cells, tissues, or …
membrane plasticity, and trafficking. Alterations of the lipid composition in cells, tissues, or …