[HTML][HTML] Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

[HTML][HTML] Programmed cell death tunes tumor immunity

J Liu, M Hong, Y Li, D Chen, Y Wu, Y Hu - Frontiers in Immunology, 2022 - frontiersin.org
The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …

New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

Tumor immune microenvironment lncRNAs

EG Park, SJ Pyo, Y Cui, SH Yoon… - Briefings in …, 2022 - academic.oup.com
Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …

[HTML][HTML] The crosstalk between tumor cells and the immune microenvironment in breast cancer: implications for immunotherapy

V Salemme, G Centonze, F Cavallo, P Defilippi… - Frontiers in …, 2021 - frontiersin.org
Breast cancer progression is a complex process controlled by genetic and epigenetic factors
that coordinate the crosstalk between tumor cells and the components of tumor …

[HTML][HTML] Isolation and characterization of exosomes for cancer research

L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

Cancer metabolism and tumor microenvironment: fostering each other?

Y Yuan, H Li, W Pu, L Chen, D Guo, H Jiang… - Science China Life …, 2022 - Springer
The changes associated with malignancy are not only in cancer cells but also in
environment in which cancer cells live. Metabolic reprogramming supports tumor cell high …

The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities

U Mehraj, RA Ganai, MA Macha, A Hamid, MA Zargar… - Cellular Oncology, 2021 - Springer
Background Breast cancer (BC), the second most common cause of cancer-related deaths,
remains a significant threat to the health and wellness of women worldwide. The tumor …

Exosomes as mediators of immune regulation and immunotherapy in cancer

FG Kugeratski, R Kalluri - The FEBS Journal, 2021 - Wiley Online Library
Exosomes are nanosized extracellular vesicles of endosomal origin that enclose a multitude
of functional biomolecules. Exosomes have emerged as key players of intercellular …

[HTML][HTML] Gamma delta T-cell-based immune checkpoint therapy: attractive candidate for antitumor treatment

Z Gao, Y Bai, A Lin, A Jiang, C Zhou, Q Cheng, Z Liu… - Molecular Cancer, 2023 - Springer
As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of
immunotherapy in recent years. They have extraordinary antitumor potential and prospects …