Traditional approaches to prevention of the complications of type 2 diabetes (T2D) and
obesity have focused on reduction of blood glucose and body weight. The development of …

Introduction Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver
disease, with type 2 diabetes mellitus (T2DM) as a major predictor. Insulin resistance and …

Background Data are scarce regarding the development of hepatic decompensation in
patients with non-alcoholic fatty liver disease (NAFLD) with and without type 2 diabetes. We …

Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic
metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular …

Background Recent studies suggest that tirzepatide, a dual glucose-dependent
insulinotropic-peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA), has …

Green tea polyphenols have numerous functions including antioxidation and modulation of
various cellular proteins and are thus beneficial against metabolic diseases including …

The 21st century is characterized by an increasing incidence and prevalence of obesity and
the burden of its associated comorbidities, especially cardiometabolic diseases, which are …

Weight regain after weight loss is a major challenge in the treatment of obesity. Immune cells
adapt to fluctuating nutritional stress, but their roles in regulating weight regain remain …

Metabolic diseases, featured with dysregulated energy homeostasis, have become major
global health challenges. Patients with metabolic diseases have high probability to manifest …

Abstract The relationship between Serum Uric Acid (UA) and Cardiovascular (CV) diseases
has already been extensively evaluated, and it was found to be an independent predictor of …