The vermiform appendix is the primary site of several distinctive benign and malignant
neoplasms. Some can produce the clinical syndrome of pseudomyxoma peritonei (PMP). A …

G protein‐coupled receptors (GPCRs) and heterotrimeric G proteins play central roles in a
diverse array of cellular processes. As such, dysregulation of GPCRs and their coupled …

Many of the fundamental concepts of signal transduction and kinase activity are attributed to
the discovery and crystallization of cAMP-dependent protein kinase, or protein kinase A …

Background Mucinous ovarian tumors are an unusual group of rare neoplasms with an
apparently clear progression from benign to borderline to carcinoma, yet with a controversial …

Despite advances in our understanding of appendiceal mucinous neoplasms and their
relationship to the pseudomyxoma peritonei syndrome, the classification of mucinous tumors …

PURPOSE Appendiceal adenocarcinomas (ACs) are rare, histologically diverse
malignancies treated as colorectal cancers despite having distinct biology and clinical …

Purpose: The natural history and prognosis of appendiceal adenocarcinomas differ from
those of adenocarcinomas arising in other large bowel sites. We aimed to compare the …

Appendiceal neoplasms include a heterogeneous group of epithelial and nonepithelial
tumors that exhibit varying malignant potential. This review article summarizes current …

Primary ovarian mucinous tumors can be difficult to distinguish from metastatic
gastrointestinal neoplasms by histology alone. The expected immunoprofile of a suspected …

Background Mucinous neoplasms of the appendix (MNA) are rare tumors which may
progress from benign to malignant disease with an aggressive biological behavior. MNA is …