Oculomics analysis in multiple sclerosis: Current ophthalmic clinical and imaging biomarkers

A Suh, G Hampel, A Vinjamuri, J Ong, SA Kamran… - Eye, 2024 - nature.com
Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central
nervous system (CNS) characterized by inflammation, demyelination, and axonal damage …

Retinal optical coherence tomography measures in multiple sclerosis: a systematic review and meta‐analysis

NK El Ayoubi, A Ismail, F Fahd… - Annals of Clinical …, 2024 - Wiley Online Library
Spectral domain‐optical coherence tomography plays a crucial role in the early detection
and monitoring of multiple sclerosis (MS) pathophysiology. We aimed to quantify differences …

Acriflavine, a HIF-1 inhibitor, preserves vision in an experimental autoimmune encephalomyelitis model of optic neuritis

JJ Anders, BW Elwood, RH Kardon… - Frontiers in …, 2023 - frontiersin.org
Introduction Optic neuritis (ON) is often an early sign of multiple sclerosis (MS), and recent
studies show a link between HIF-1 pathway activation and inflammation. This study aimed to …

Multiple Sclerosis in the Digital Health Age: Challenges and Opportunities-A Systematic Review

B Specht, H Jager, S Garbaya, A Pincherle, PA Sarvari… - medRxiv, 2023 - medrxiv.org
In recent times, we have unequivocally witnessed a push towards digitising the healthcare
system. Topics such as remote patient monitoring (RPM), digital health, and their use to …

Der Stellenwert funktioneller Outcome-Parameter des afferent visuellen Systems bei neuroinflammatorischen Erkrankungen

LM Manthey, GS Buenrostro, F Paul… - Klinische …, 2024 - thieme-connect.com
Störungen des afferenten visuellen Systems sind seit Langem bei diversen neurologischen
Erkrankungen beschrieben. Somit ist auch die Untersuchung des visuellen Systems ein …

Untersuchungen des visuellen Systems zur Diagnose und Prognose neuroinflammatorischer Erkrankungen

S Sellathurai, M Hardmeier… - Klinische …, 2024 - thieme-connect.com
The visual system is frequently affected in neuroinflammatory diseases. While the typical
clinical manifestation is optic neuritis (ON), lesions along the entire visual pathway are …

The Study of Remyelinating Therapies in Multiple Sclerosis: Visual Outcomes as a Window Into Repair

LR Zuroff, AJ Green - Journal of Neuro-Ophthalmology, 2022 - journals.lww.com
Methods: A review of key literature plus additional targeted search of PubMed and Google
Scholar was conducted. Results: There has been a rapid expansion of clinical trials studying …

Optic Nerve Imaging in Multiple Sclerosis and Related Disorders

À Rovira, A Vidal-Jordana, C Auger… - Neuroimaging …, 2024 - neuroimaging.theclinics.com
Three dimensional double inversion recovery is likely the most sensitive MR imaging
sequence for identifying demyelinating lesions of the optic nerve, capable of detecting …