BK virus infection: an update on diagnosis and treatment

D Sawinski, S Goral - Nephrology Dialysis Transplantation, 2015 - academic.oup.com
BK virus, first isolated in 1971, is a significant risk factor for renal transplant dysfunction and
allograft loss. Unfortunately, treatment options for BK virus infection are limited, and there is …

Clinical role of the renal transplant biopsy

WW Williams, D Taheri, N Tolkoff-Rubin… - Nature Reviews …, 2012 - nature.com
Percutaneous needle core biopsy is the definitive procedure by which essential diagnostic
and prognostic information on acute and chronic renal allograft dysfunction is obtained. The …

BK polyomavirus in solid organ transplantation—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

HH Hirsch, PS Randhawa… - Clinical …, 2019 - Wiley Online Library
The present AST‐IDCOP guidelines update information on BK polyomavirus (BKP yV)
infection, replication, and disease, which impact kidney transplantation (KT), but rarely non …

[HTML][HTML] BK polyomavirus in solid organ transplantation

HH Hirsch, P Randhawa… - American journal of …, 2013 - Elsevier
The human BK polyomavirus (BKV) is the major cause of polyomavirus-associated
nephropathy (PyVAN) putting 1–15% of kidney transplant patients at risk of premature …

The Banff Working Group classification of definitive polyomavirus nephropathy: morphologic definitions and clinical correlations

V Nickeleit, HK Singh, P Randhawa… - Journal of the …, 2018 - journals.lww.com
Polyomavirus nephropathy (PVN) is a common viral infection of renal allografts, with biopsy-
proven incidence of approximately 5%. A generally accepted morphologic classification of …

European perspective on human polyomavirus infection, replication and disease in solid organ transplantation

HH Hirsch, N Babel, P Comoli, V Friman… - Clinical Microbiology …, 2014 - Wiley Online Library
Human polyomaviruses (HP yVs) are a growing challenge in immunocompromised patients
in view of the increasing number of now 12 HP yV species and their diverse disease …

[HTML][HTML] BK virus nephropathy: histological evolution by sequential pathology

BJ Nankivell, J Renthawa, RN Sharma, K Kable… - American Journal of …, 2017 - Elsevier
Reactivation of BK virus in renal allografts causes a destructive chronic infection. This single-
center retrospective cohort study describes the evolution of BK virus allograft nephropathy …

The human polyomavirus BK (BKP yV): virological background and clinical implications

CH Rinaldo, GD Tylden, BN Sharma - Apmis, 2013 - Wiley Online Library
Polyomavirus BK (BKPyV) infects most people subclinically during childhood and
establishes a lifelong infection in the renourinary tract. In most immunocompetent …

Dynamic viral integration patterns actively participate in the progression of BK polyomavirus-associated diseases after renal transplantation

Y Wang, S Yan, Y Liu, Z Yan, W Deng, J Geng… - American Journal of …, 2023 - Elsevier
The classical lytic infection theory along with large T antigen-mediated oncogenesis cannot
explain the BK polyomavirus (BKPyV)-associated tumor secondary to BKPyV-associated …

Incidence and outcomes of BK virus allograft nephropathy among ABO-and HLA-incompatible kidney transplant recipients

A Sharif, N Alachkar, S Bagnasco… - Clinical journal of the …, 2012 - journals.lww.com
Results Risk for BKVAN was greater among ABO-incompatible than HLA-incompatible
patients (17.7% versus 5.9%; P= 0.008). Of BKVAN cases, 42% were subclinical, diagnosed …