Crystallization is one of the most important unit operations used for the separation and
purification of crystalline solid products. Appropriate design and control of the crystallization …

The academic literature on and industrial practice of control of solution crystallization
processes have seen major advances in the past 15 years that have been enabled by …

Crystallization is an important part of many chemical industries. Efforts are being invested to
improve the performance of the crystallization process by designing novel crystallizers. An …

Control of polymorphism of the enantiotropic p-aminobenzoic acid at either the α or β
polymorph while maintaining high yield was achieved by mixed suspension mixed product …

This work details the estimation of the secondary nucleation kinetics of paracetamol in
ethanol solutions for cooling crystallisation processes, by means of isothermal under …

Size, shape, and polymorphic form are the critical attributes of crystalline particles and
represent the major focus of today's crystallization process design. This work demonstrates …

In this work, a diffusion-theory-based model has been devised to simulate dissolution
kinetics of a poorly water-soluble drug, ibuprofen. The model was developed from the Noyes …

Secondary nucleation (eg due to attrition) and accidental seeding (eg from crust on the wall
of vessels) are undesired events that often take place during industrial crystallization …

The nucleation of the metastable form of a substance or of a mixture of more forms is very
common in polymorphic crystallization. Additionally, in industry seed may contain a variable …

Characteristics of crystal quality, including crystal size distribution, size, morphology,
polymorphism and chirality, have been established as important indicators of crystalline …