[HTML][HTML] Synthesis of novel spirochromane incorporating Schiff's bases, potential antiproliferative activity, and dual EGFR/HER2 inhibition: Cell cycle analysis and in …

DIA Othman, A Hamdi, WM Elhusseiny… - Saudi Pharmaceutical …, 2023 - Elsevier
Spirochromanes incorporating Schiff's bases and semicarbazones 4a-e and 5a-j were
synthesizedand analyzed for their potential antiproliferative activity using four human cancer …

Synthesis of Novel Benzenesulfonamide-Bearing Functionalized Imidazole Derivatives as Novel Candidates Targeting Multidrug-Resistant Mycobacterium abscessus …

B Balandis, P Kavaliauskas, B Grybaitė, V Petraitis… - Microorganisms, 2023 - mdpi.com
Infections caused by drug-resistant (DR) Mycobacterium abscessus (M. abscessus) complex
(MAC) are an important public health concern, particularly when affecting individuals with …

Discovery of gefitinib-1, 2, 3-triazole derivatives against lung cancer via inducing apoptosis and inhibiting the colony formation

E Gao, Y Wang, G Fan, G Xu, ZY Wu, ZJ Liu, JC Liu… - Scientific Reports, 2024 - nature.com
A series of 20 novel gefitinib derivatives incorporating the 1, 2, 3-triazole moiety were
designed and synthesized. The synthesized compounds were evaluated for their potential …