Alternative splicing (AS) is a key process in which precursor RNAs produce different mature
RNAs, and the disorder of AS is a key factor in promoting cancer development. Compared …

Long non-coding RNAs (lncRNAs) are the key components of non-coding RNAs (ncRNAs)
with a length of 200 nucleotides. They are transcribed from the so-called “dark matter” of the …

Exosomes are mobile extracellular vesicles with a diameter 40 to 150 nm. They play a
critical role in several processes such as the development of cancers, intercellular signaling …

Background Cancer is associated with various genetic and environmental risk factors.
Beside the mutations or aberrant expression of protein-coding genes, the genetic …

Background Novel therapies tailored to the molecular composition of esophageal squamous
cell carcinoma (ESCC) are needed to improve patient survival. We investigated the …

Long non‑coding RNAs are associated with cancer progression. Long intergenic non‑
protein coding RNA (linc)‑regulator of reprogramming (ROR) enhances tumor development …

Long noncoding RNAs (lncRNAs) undergo extensive alternative splicing, but little is known
about isoform functions. A prior investigation of lncRNA RP11-369C8. 1 reported that its …

Cancer is responsible for more than 10 million deaths every year. Metastasis and drug
resistance lead to a poor survival rate and are a major therapeutic challenge. Substantial …

Despite the availability of modern techniques for the treatment of esophageal squamous cell
carcinoma (ESCC), tumor recurrence and metastasis are significant challenges in clinical …

Alterations in the expression level of the MYC gene are often found in the cells of various
malignant tumors. Overexpressed MYC has been shown to stimulate the main processes of …