Small‐Molecule Quenchers for Förster Resonance Energy Transfer: Structure, Mechanism, and Applications

B Fang, Y Shen, B Peng, H Bai, L Wang… - Angewandte …, 2022 - Wiley Online Library
For fluorogenic probes, Förster resonance energy transfer (FRET) is one of the most widely
used mechanisms to realize the detection of biochemical activities. Dark quenchers relax …

Acyldepsipeptide analogues: a future generation antibiotics for tuberculosis treatment

SZZ Cobongela, MM Makatini, PS Mdluli, NRS Sibuyi - Pharmaceutics, 2022 - mdpi.com
Acyldepsipeptides (ADEPs) are a new class of emerging antimicrobial peptides (AMPs),
which are currently explored for treatment of pathogenic infections, including tuberculosis …

RbfA and IF3 couple ribosome biogenesis and translation initiation to increase stress tolerance

IM Sharma, SA Woodson - Nucleic Acids Research, 2020 - academic.oup.com
Bacterial ribosome biogenesis and translation occur in the same cellular compartment.
Therefore, a biochemical gate-keeping step is required to prevent error-prone immature …

[HTML][HTML] Undecanoic acid, lauric acid, and N-tridecanoic acid inhibit Escherichia coli persistence and biofilm formation

X Jin, J Zhou, G Richey, M Wang… - … of microbiology and …, 2021 - ncbi.nlm.nih.gov
Persister cell formation and biofilms of pathogens are extensively involved in the
development of chronic infectious diseases. Eradicating persister cells is challenging, owing …

A complementary mechanism of bacterial mRNA translation inhibition by tetracyclines

V Barrenechea, M Vargas-Reyes, M Quiliano… - Frontiers in …, 2021 - frontiersin.org
Tetracycline has positively impacted human health as well as the farming and animal
industries. Its extensive usage and versatility led to the spread of resistance mechanisms …

[HTML][HTML] Antimicrobial and antibiotic-resistance reversal activity of some medicinal plants from Cameroon against selected resistant and non-resistant uropathogenic …

MMJ Arsene, PI Viktorovna, AKL Davares… - Frontiers in Bioscience …, 2022 - imrpress.com
Background and Aim: Antibiotics' resistance is the leading cause of complications in the
treatment of urinary tract infections. This study aimed to screen the antimicrobial potential of …

Quantitative proteomics reveals the antibiotics adaptation mechanism of Aeromonas hydrophila under kanamycin stress

L Zhang, X Chen, G Wang, J Yao, J Wei, Z Liu, X Lin… - Journal of …, 2022 - Elsevier
Aeromonas hydrophila is a widespread opportunistic pathogen of aquatic fishes in
freshwater habitats. The current emergence of antimicrobial-resistant A. hydrophila has …

Antibiotics targeting the 30S ribosomal subunit: a lesson from nature to find and develop new drugs

AM Giuliodori, R Spurio, P Milón… - Current Topics in …, 2018 - ingentaconnect.com
The use of antibiotics has revolutionized medicine, greatly improving our capacity to save
millions of lives from otherwise deadly bacterial infections. Unfortunately, the health …

DNA aptamers for the recognition of HMGB1 from Plasmodium falciparum

DF Joseph, JA Nakamoto, OA Garcia Ruiz… - PloS one, 2019 - journals.plos.org
Rapid Diagnostic Tests (RDTs) for malaria are restricted to a few biomarkers and antibody-
mediated detection. However, the expression of commonly used biomarkers varies …

Exploring antibiotic resistance mechanisms in Mycobacterium abscessus for enhanced therapeutic approaches

TQ Nguyen, BE Heo, S Jeon, A Ash, H Lee… - Frontiers in …, 2024 - frontiersin.org
Mycobacterium abscessus, a leading cause of severe lung infections in
immunocompromised individuals, poses significant challenges for current therapeutic …