mRNA Cancer vaccines: construction and boosting strategies

X Liu, P Huang, R Yang, H Deng - ACS nano, 2023 - ACS Publications
In late 2020, the US Food and Drug Administration (FDA) approved a lipid-based mRNA
vaccine for the prevention of COVID-19, which has pushed this field to be more closely …

Navigating the Immune Maze: Pioneering Strategies for Unshackling Cancer Immunotherapy Resistance

L Yao, Q Wang, W Ma - Cancers, 2023 - mdpi.com
Simple Summary Cancer treatments have made remarkable advances with the introduction
of immunotherapy, which recruits the body's immune system to fight cancer. Despite these …

Revolutionizing Cancer Treatment: Unleashing the Power of Viral Vaccines, Monoclonal Antibodies, and Proteolysis-Targeting Chimeras in the New Era of …

P Mohite, V Yadav, R Pandhare, S Maitra, FM Saleh… - ACS …, 2024 - ACS Publications
In the realm of cancer immunotherapy, a profound evolution has ushered in sophisticated
strategies that encompass both traditional cancer vaccines and emerging viral vaccines …

Overcoming suppressive tumor microenvironment by vaccines in solid tumor

YJ Xie, WQ Liu, D Li, JC Hou, PS Coghi, XX Fan - Vaccines, 2023 - mdpi.com
Conventional vaccines are widely used to boost human natural ability to defend against
foreign invaders, such as bacteria and viruses. Recently, therapeutic cancer vaccines …

Harnessing biomaterial architecture to drive anticancer innate immunity

MA Davis, E Cho, MH Teplensky - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Immunomodulation is a powerful therapeutic approach that harnesses the body's own
immune system and reprograms it to treat diseases, such as cancer. Innate immunity is key …

Components, Formulations, Deliveries, and Combinations of Tumor Vaccines

T Liu, W Yao, W Sun, Y Yuan, C Liu, X Liu, X Wang… - ACS …, 2024 - ACS Publications
Tumor vaccines, an important part of immunotherapy, prevent cancer or kill existing tumor
cells by activating or restoring the body's own immune system. Currently, various …

Advancing Cancer Immunotherapy: The Potential of mRNA Vaccines As a Promising Therapeutic Approach

F Goyal, A Chattopadhyay, U Navik, A Jain… - Advanced …, 2024 - Wiley Online Library
Abstract mRNA vaccines have long been recognized for their ability to induce robust
immune responses. The discovery that mRNA vaccines may also contribute to antitumor …

Modification with Conventional Surfactants to Improve a Lipid-Based Ionic-Liquid-Associated Transcutaneous Anticancer Vaccine

S Uddin, MR Islam, RM Moshikur, R Wakabayashi… - Molecules, 2023 - mdpi.com
Transcutaneous vaccination is one of the successful, affordable, and patient-friendly
advanced immunization approaches because of the presence of multiple immune …

Targeting Neoantigens in Pancreatic Ductal Adenocarcinoma

G Singh, D Kutcher, R Lally, V Rai - Cancers, 2024 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of
cancer deaths in the United States due to its late-stage diagnosis. Currently, there are no …

Exosome-like Systems: From Therapies to Vaccination for Cancer Treatment and Prevention—Exploring the State of the Art

HH Sheikhhossein, F Iommelli, N Di Pietro, MC Curia… - Vaccines, 2024 - mdpi.com
Cancer remains one of the main causes of death in the world due to its increasing incidence
and treatment difficulties. Although significant progress has been made in this field …