Ocular drug delivery has been a major challenge to pharmacologists and drug delivery
scientists due to its unique anatomy and physiology. Static barriers (different layers of …

Substantial evidence indicates that microRNA-155 (miR-155) plays a crucial role in the
pathogenesis of diabetes mellitus (DM) and its complications. A number of clinical studies …

Integrin binding to bioengineered hydrogel scaffolds is essential for tissue regrowth and
regeneration, yet not all integrin binding can lead to tissue repair. Here, we show that …

Retinal and choroidal neovascularization are a major cause of significant visual impairment,
worldwide. Understanding the various factors involved in the accompanying …

Diabetes mellitus is a serious health problem that affects over 350 million individuals
worldwide. Diabetic retinopathy (DR), which is the most common microvascular complication …

Posterior segment diseases, such as age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are vital factor that seriously threatens human vision health and quality of …

There is a requirement for efficacious and safe medicines to treat diseases with high unmet
need. The resurgence in αv‐RGD integrin inhibitor drug discovery is poised to contribute to …

Integrins are a class of transmembrane receptors that are involved in a wide range of
biological functions. Dysregulation of integrins has been implicated in many pathological …

Treating posterior segment and retinal diseases poses challenges due to the complex
structures in the eye that act as robust barriers, limiting medication delivery and …

Age-related ocular diseases, such as age-related macular degeneration (AMD), diabetic
retinopathy, and glaucoma, result in life-long functional deficits and enormous global health …