For many decades, the thiazole moiety has been an important heterocycle in the world of
chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) …

Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …

Alzheimer's disease (AD) is a multifactorial irreversible neurological disorder which results
in cognitive impairment, loss of cholinergic neurons in synapses of the basal forebrain and …

Neurodegenerative diseases represent nowadays one of the major health problems.
Despite the efforts made to unveil the mechanism leading to neurodegeneration, it is still not …

Thiazole derivatives remains honored heterocycles in the field of medicinal chemistry. This
scaffold has been proven as a universal motif that is present in numerous pharmacologically …

Cholinesterase enzymes such as acetylcholinesterase (AChE) and butyrylcholinesterase
(BuChE) cause hydrolysis of acetylcholine (ACh), a neurotransmitter responsible for the …

In last few decades, nitrogen‐containing heterocycles have maintained their status as an
important core of FDA‐approved drugs and medicinally active compounds. Quinoxaline is …

A straightforward method has been developed to synthesize 2-aryl-3-(2-aminoaryl)
quinoxalines from 2-arylindoles and 1, 2-diaminoarenes under mild electrochemical …

The accumulation of amyloid-β (Aβ) is the main event related to Alzheimer's disease (AD)
progression. Over the years, several disease-modulating approaches have been reported …

A mild oxidative sequential tandem reaction was developed to rapidly generate 2-aryl-3-(2-
aminoaryl) quinoxalines. This method exploited 2-substituted indoles as substrate to form …