The global epidemiology of chikungunya from 1999 to 2020: A systematic literature review to inform the development and introduction of vaccines

AA Bettis, M L'Azou Jackson, IK Yoon… - PLoS neglected …, 2022 - journals.plos.org
Chikungunya fever is an acute febrile illness that is often associated with severe
polyarthralgia in humans. The disease is caused by chikungunya virus (CHIKV), a mosquito …

[HTML][HTML] An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral

JG Julander, JF Demarest, R Taylor, BB Gowen… - Antiviral research, 2021 - Elsevier
Galidesivir (BCX4430) is an adenosine nucleoside analog that is broadly active in cell
culture against several RNA viruses of various families. This activity has also been shown in …

Functions of astrocytes under normal conditions and after a brain disease

SL Valles, SK Singh, J Campos-Campos… - International Journal of …, 2023 - mdpi.com
In the central nervous system (CNS) there are a greater number of glial cells than neurons
(between five and ten times more). Furthermore, they have a greater number of functions …

Emerging and re-emerging pediatric viral diseases: a continuing global challenge

SA Hoffman, YA Maldonado - Pediatric Research, 2024 - nature.com
The twenty-first century has been marked by a surge in viral epidemics and pandemics,
highlighting the global health challenge posed by emerging and re-emerging pediatric viral …

Aedes Mosquito Salivary Components and Their Effect on the Immune Response to Arboviruses

D Guerrero, T Cantaert, D Missé - Frontiers in cellular and infection …, 2020 - frontiersin.org
Vector-borne diseases are responsible for over a billion infections each year and nearly one
million deaths. Mosquito-borne dengue virus, West Nile, Japanese encephalitis, Zika …

Drug repurposing: A strategy for discovering inhibitors against emerging viral infections

IJ dos Santos Nascimento… - Current Medicinal …, 2021 - ingentaconnect.com
Background: Viral diseases are responsible for several deaths around the world. Over the
past few years, the world has seen several outbreaks caused by viral diseases that, for a …

Paper based DNA biosensor for detection of chikungunya virus using gold shells coated magnetic nanocubes

C Singhal, A Dubey, A Mathur, CS Pundir, J Narang - Process Biochemistry, 2018 - Elsevier
Abstract Electrochemical DNA (E-DNA) sensors have attracted large attention, as they play
an important role in early diagnosis of infectious diseases. Herein, we have rationally …

Organometallic complex strongly impairs chikungunya virus entry to the host cells

DM Oliveira, IA Santos, DOS Martins… - Frontiers in …, 2020 - frontiersin.org
Chikungunya fever is a disease caused by the Chikungunya virus (CHIKV) that is
transmitted by the bite of the female of Aedes sp. mosquito. The symptoms include fever …

Serological and spatial analysis of alphavirus and flavivirus prevalence and risk factors in a rural community in western Kenya

EN Grossi-Soyster, EAJ Cook… - PLoS neglected …, 2017 - journals.plos.org
Alphaviruses, such as chikungunya virus, and flaviviruses, such as dengue virus, are (re)-
emerging arboviruses that are endemic in tropical environments. In Africa, arbovirus …

[HTML][HTML] Molecular characteristics and replication mechanism of dengue, zika and chikungunya arboviruses, and their treatments with natural extracts from plants: An …

AK Rodriguez, AL Muñoz, NA Segura, HR Rangel… - EXCLI …, 2019 - ncbi.nlm.nih.gov
Viruses transmitted by arthropods (arboviruses) are the etiological agents of several human
diseases with worldwide distribution; including dengue (DENV), zika (ZIKV), yellow fever …