Drug repositioning for orphan diseases

D Sardana, C Zhu, M Zhang… - Briefings in …, 2011 - academic.oup.com
The need and opportunity to discover therapeutics for rare or orphan diseases are
enormous. Due to limited prevalence and/or commercial potential, of the approximately …

Semantic web meets integrative biology: a survey

H Chen, T Yu, JY Chen - Briefings in bioinformatics, 2013 - academic.oup.com
Integrative Biology (IB) uses experimental or computational quantitative technologies to
characterize biological systems at the molecular, cellular, tissue and population levels. IB …

Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data

B Chen, X Dong, D Jiao, H Wang, Q Zhu, Y Ding… - BMC …, 2010 - Springer
Background Recently there has been an explosion of new data sources about genes,
proteins, genetic variations, chemical compounds, diseases and drugs. Integration of these …

Assessing drug target association using semantic linked data

B Chen, Y Ding, DJ Wild - PLoS computational biology, 2012 - journals.plos.org
The rapidly increasing amount of public data in chemistry and biology provides new
opportunities for large-scale data mining for drug discovery. Systematic integration of these …

Results of the ontology alignment evaluation initiative 2010

J Euzenat, A Ferrara, C Meilicke, A Nikolov, J Pane… - 2011 - eprints.biblio.unitn.it
Ontology matching consists of finding correspondences between entities of two ontologies.
OAEI campaigns aim at comparing ontology matching systems on precisely defined test …

Scalable and distributed methods for entity matching, consolidation and disambiguation over linked data corpora

A Hogan, A Zimmermann, J Umbrich, A Polleres… - Journal of Web …, 2012 - Elsevier
With respect to large-scale, static, Linked Data corpora, in this paper we discuss scalable
and distributed methods for entity consolidation (aka. smushing, entity resolution, object …

The Translational Medicine Ontology and Knowledge Base: driving personalized medicine by bridging the gap between bench and bedside

JS Luciano, B Andersson, C Batchelor… - Journal of biomedical …, 2011 - Springer
Background Translational medicine requires the integration of knowledge using
heterogeneous data from health care to the life sciences. Here, we describe a collaborative …

Finding complex biological relationships in recent PubMed articles using Bio-LDA

H Wang, Y Ding, J Tang, X Dong, B He, J Qiu, DJ Wild - PloS one, 2011 - journals.plos.org
The overwhelming amount of available scholarly literature in the life sciences poses
significant challenges to scientists wishing to keep up with important developments related …

Emerging practices for mapping and linking life sciences data using RDF—A case series

MS Marshall, R Boyce, HF Deus, J Zhao… - Journal of Web …, 2012 - Elsevier
Members of the W3C Health Care and Life Sciences Interest Group (HCLS IG) have
published a variety of genomic and drug-related data sets as Resource Description …

A more decentralized vision for linked data

A Polleres, MR Kamdar, JD Fernández… - Semantic …, 2020 - content.iospress.com
In this deliberately provocative position paper, we claim that more than ten years into Linked
Data there are still (too?) many unresolved challenges towards arriving at a truly machine …