While antibiotics are clearly important treatments for infection, antibiotic-induced modulation
of the immune system can have detrimental effects on pathogen clearance and immune …

The vicious cycle is that hyperglycemia (≥ 11.1 mmol/l) or other diabetes-associated factors
facilitate or worsen the development of infections and vice versa, the infections deteriorate …

Herein, a conductivity method was engaged to explore the effects of a fluoroquinolone drug,
namely ciprofloxacin hydrochloride (CFH)/CFH+ polyols (organic compounds with multiple …

Objective: Use of antibiotics in critically ill patients may increase the risk of invasive Candida
infection. The objective of this study was to determine whether increased exposure to …

Ticks are notorious hematophagous ectoparasites and vectors of many deadly pathogens.
As an effective vector, ticks must break the strong barrier provided by the skin of their host …

The use of norfloxacin either as primary or secondary prophylaxis of bacterial infections in
advanced cirrhosis has improved patient's survival. This may be explained not only due to a …

Respiratory virus infections, including infections with rhinoviruses (RVs), are related to
exacerbations of chronic obstructive pulmonary disease (COPD). A new quinolone …

Background/Aims: Excessive production of advanced glycation end products (AGEs) has
been implicated in diabetes-related complications. This study aimed to investigate the …

Drug features that are associated with Stevens-Johnson syndrome (SJS) have not been fully
characterized. A molecular target analysis of the drugs associated with SJS in the FDA …

Introduction and aim: Sepsis is defined as life-threatening organ dysfunction caused by a
dysregulated host response to infection. In the absence of host-modulating therapies …