Seven ligands bind to and activate the mammalian epidermal growth factor (EGF) receptor
(EGFR/ERBB1/HER1): EGF, transforming growth factor-alpha (TGFA), heparin-binding EGF …

Among the extensive public and scientific interest in the use of phytochemicals to prevent or
treat human diseases in recent years, natural compounds have been highly investigated to …

The abnormal misfolding and aggregation of amyloid-β (Aβ) peptides into β-sheet enriched
insoluble deposits initiates a cascade of events leading to pathological processes and …

Introduction: Curcumin, a dietary polyphenol found in the curry spice turmeric, possesses
potent antioxidant and anti-inflammatory properties and an ability to modulate multiple …

The positive role of nutrition in chronic neurodegenerative diseases (NDs) suggests that
dietary interventions represent helpful tools for preventing NDs. In particular, diets enriched …

Amyloid beta-protein (Aβ) is the major component of senile plaques and cerebrovascular
amyloid deposits in individuals with Alzheimer's disease. Aβ is known to increase free …

Background Aging is accompanied by increasing vulnerability to pathologies such as
atherosclerosis (ATH) and Alzheimer disease (AD). Are these different pathologies, or …

Alzheimer's disease (AD) is a major health problem worldwide, with no effective treatment
approach. Curcumin is the main ingredient of turmeric traditionally used in Asian medicine …

As demographics in developed nations shift towards an aging population,
neurodegenerative pathologies, especially dementias such as Alzheimer's disease, pose …

Alzheimer's disease (AD) is the most common form of dementia. There is limited choice in
modern therapeutics, and drugs available have limited success with multiple side effects in …