Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies
This narrative review represents an output from the International Association for the Study of
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …
Pain's global task force on the use of cannabis, cannabinoids, and cannabis-based …
[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission
M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
Distribution of cannabinoid receptors in the central and peripheral nervous system
K Mackie - Cannabinoids, 2005 - Springer
CB 1 cannabinoid receptors appear to mediate most, if not all of the psychoactive effects of
delta-9-tetrahydrocannabinol and related compounds. This G protein-coupled receptor has …
delta-9-tetrahydrocannabinol and related compounds. This G protein-coupled receptor has …
The endocannabinoid system and pain
J Guindon, AG Hohmann - CNS & Neurological Disorders-Drug …, 2009 - ingentaconnect.com
The therapeutic potential of cannabinoids has been the topic of extensive investigation
following the discovery of cannabinoid receptors and their endogenous ligands …
following the discovery of cannabinoid receptors and their endogenous ligands …
The role of the endocannabinoid system in the brain–gut axis
KA Sharkey, JW Wiley - Gastroenterology, 2016 - Elsevier
The actions of cannabis are mediated by receptors that are part of an endogenous
cannabinoid system. The endocannabinoid system (ECS) consists of the naturally occurring …
cannabinoid system. The endocannabinoid system (ECS) consists of the naturally occurring …
Cannabis-based medicines and pain: a review of potential synergistic and entourage effects
U Anand, B Pacchetti, P Anand… - Pain management, 2021 - Taylor & Francis
The recent legalization of medicinal cannabis in several jurisdictions has spurred the
development of therapeutic formulations for chronic pain. Unlike pure delta-9 …
development of therapeutic formulations for chronic pain. Unlike pure delta-9 …
Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures—a short review
I Svíženská, P Dubový, A Šulcová - Pharmacology Biochemistry and …, 2008 - Elsevier
In the last 25 years data has grown exponentially dealing with the discovery of the
endocannabinoid system consisting of specific cannabinoid receptors, their endogenous …
endocannabinoid system consisting of specific cannabinoid receptors, their endogenous …
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors
Although endocannabinoids constitute one of the first lines of defense against pain, the
anatomical locus and the precise receptor mechanisms underlying cannabinergic …
anatomical locus and the precise receptor mechanisms underlying cannabinergic …
Distribution of the endocannabinoid system in the central nervous system
SSJ Hu, K Mackie - Endocannabinoids, 2015 - Springer
The endocannabinoid system consists of endogenous cannabinoids (endocannabinoids),
the enzymes that synthesize and degrade endocannabinoids, and the receptors that …
the enzymes that synthesize and degrade endocannabinoids, and the receptors that …
Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain
Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels
have been proposed to act as metabotropic and ionotropic receptors, respectively, for two …
have been proposed to act as metabotropic and ionotropic receptors, respectively, for two …