Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

B cells are capable of a wide range of effector functions including antibody secretion,
antigen presentation, cytokine production, and generation of immunological memory. A …

Allergen-specific immunoglobulin E (IgE) antibodies mediate pathology in diseases such as
allergic rhinitis and food allergy. Memory B cells (MBCs) contribute to circulating IgE by …

The achievement of long‐lasting, safe treatments for food allergy is dependent on the
understanding of the immunological basis of food allergy. Accurate diagnosis is essential for …

An increasing number of people suffer from IgE‐mediated food allergies. The immunological
mechanisms that cause IgE‐mediated food allergy have been extensively studied. B cells …

IgE-mediated food allergy affects 6–8% of the population in the United States. Type 2
immune responses are central to the pathogenesis of food allergy, but type 2 CD4+ T cell …

About 20 years after the identification of immunoglobulin E (IgE) and its key role in allergic
hypersensitivity reactions against normally harmless substances, scientists have started …

B cells generate antibodies that provide protection from infection, but also cause pathology
in autoimmune and allergic conditions. Antigen-specific B cells can be detected by binding …

Stringent regulation of IgE antibody production is critical for constraining allergic responses.
This review discusses recent advances in understanding cell-intrinsic and extrinsic …