Birth defects contribute to∼ 0.3% of global infant mortality in the first month of life, and
congenital heart disease (CHD) is the most common birth defect among newborns …

Abstract Purpose of Review Congenital heart disease (CHD) is the most frequently occurring
birth defect. Majority of the earlier reviews focussed on the association of genetic factors with …

The causal genetic underpinnings of congenital heart diseases, which are often complex
and multigenic, are still far from understood. Moreover, there are also predominantly …

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. Ventricular
dysfunction and cardiac arrhythmias are well-documented complications in patients with …

Congenital heart defects (CHDs) are the most common birth defect in human with an
incidence of almost 1% of all live births. Most cases have a multifactorial origin with both …

Objective Eighty percent of patients with a diagnosis of tetralogy of Fallot (TOF) do not have
a known genetic etiology or syndrome. We sought to identify key molecular pathways and …

Congenital heart disease (CHD) represents a major class of birth defects worldwide and is
associated with cardiac malformations that often require surgical intervention immediately …

Background Rare genetic variants have been identified to be important contributors to the
risk of Tetralogy of Fallot (TOF), the most common cyanotic congenital heart disease (CHD) …

Tetralogy of Fallot (TOF) is a cyanotic congenital condition contributed by genetic, epigenetic
as well as environmental factors. We applied sparse machine learning algorithms to …

Congenital heart disease (CHD) is a leading cause of birth defect-related death. Despite
significant advances, the mechanisms underlying the development of CHD are complex and …