In a normal pregnancy, maternal circulatory system presents a hypercoagulable state due to
the effect of hormone secretion. Even minor variations in fibrinolytic system could lead to …

Recurrent pregnancy loss (RPL) is a reproductive disorder defined as two or more
successive and spontaneous pregnancy losses (before 20 weeks of gestation), which affects …

Purpose Recurrent pregnancy loss (RPL) is affecting 1–4% of women who conceive
approximately, and no cause could be found in more than 50% of women suffering from …

Human plasminogen activator inhibitor‐1 (PAI‐1) is closely related to embryonic
development and pregnancy success. The association between PAI‐1 gene polymorphisms …

Plasminogen activator inhibitor type 1 (PAI-1) is a main inhibitor of fibrinolysis. The PAI-1
gene (SERPINE1) harbors genetic variants with the potential of modifying plasma levels of …

Problem Association between PAI‐1 4G/5G polymorphism and reproductive failures has
been postulated. We aimed to investigate its impact on metabolic, hormonal, and immune …

Aim: Therefore, we decided to investigate the-675 ID, 4G/5G PAI-1 as a potential genetic
factor linked to PL in European and worldwide populations. A systematic review of the …

Background Placenta-related obstetric complications (PROCs) such as miscarriage, fetal
growth restriction, preeclampsia, and preterm birth are the major causes of maternal and …

Abstract Background FXIII Val34Leu (rs5985) and β-fibrinogen-455G/A (rs1800790)
genotypes have been reported to be associated with recurrent spontaneous abortion (RSA) …

Background: Recurrent pregnancy loss (RPL) is a heterogeneous condition consisting of
two or more consecutive abortions occurring before 20 weeks of gestation. One of the …