Human platelet lysate: replacing fetal bovine serum as a gold standard for human cell propagation?
The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …
Scaled preparation of extracellular vesicles from conditioned media
S Staubach, FN Bauer, T Tertel, V Börger… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) especially of mesenchymal stem/stomal cells (MSCs) are
increasingly considered as biotherapeutic agents for a variety of different diseases. For …
increasingly considered as biotherapeutic agents for a variety of different diseases. For …
A functional corona around extracellular vesicles enhances angiogenesis, skin regeneration and immunomodulation
M Wolf, RW Poupardin, P Ebner‐Peking… - Journal of …, 2022 - Wiley Online Library
Nanoparticles can acquire a plasma protein corona defining their biological identity. Corona
functions were previously considered for cell‐derived extracellular vesicles (EVs). Here we …
functions were previously considered for cell‐derived extracellular vesicles (EVs). Here we …
Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …
cell types and participate in physiological and pathophysiological processes. EVs mediate …
Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use
GP Fadini, D Losordo, S Dimmeler - Circulation research, 2012 - Am Heart Assoc
Diverse subsets of endothelial progenitor cells (EPCs) are used for the treatment of ischemic
diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for …
diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for …
Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance
Leukemia cells are protected from chemotherapy-induced apoptosis by their interactions
with bone marrow mesenchymal stromal cells (BM-MSCs). Yet the underlying mechanisms …
with bone marrow mesenchymal stromal cells (BM-MSCs). Yet the underlying mechanisms …
Patterning human stem cells and endothelial cells with laser printing for cardiac regeneration
R Gaebel, N Ma, J Liu, J Guan, L Koch, C Klopsch… - Biomaterials, 2011 - Elsevier
Recent study showed that mesenchymal stem cells (MSC) could inhibit apoptosis of
endothelial cells in hypoxic condition, increase their survival, and stimulate the …
endothelial cells in hypoxic condition, increase their survival, and stimulate the …
Mesenchymal stem and progenitor cells in regeneration: tissue specificity and regenerative potential
It has always been an ambitious goal in medicine to repair or replace morbid tissues for
regaining the organ functionality. This challenge has recently gained momentum through …
regaining the organ functionality. This challenge has recently gained momentum through …
Steroid-induced osteonecrosis of the femoral head: novel insight into the roles of bone endothelial cells in pathogenesis and treatment
C Huang, Z Wen, J Niu, S Lin, W Wang - Frontiers in cell and …, 2021 - frontiersin.org
Steroid-induced osteonecrosis of the femoral head (SONFH) is a disease characterized by
the collapse of the femoral head. SONFH occurs due to the overuse of glucocorticoids (GCs) …
the collapse of the femoral head. SONFH occurs due to the overuse of glucocorticoids (GCs) …
Concise review: endothelial progenitor cells in regenerative medicine: applications and challenges
Endothelial progenitor cells (EPCs) are currently being studied as candidate cell sources for
revascularization strategies. Significant advances have been made in understanding the …
revascularization strategies. Significant advances have been made in understanding the …